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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">inovmed</journal-id><journal-title-group><journal-title xml:lang="ru">Инновационная медицина Кубани</journal-title><trans-title-group xml:lang="en"><trans-title>Innovative Medicine of Kuban</trans-title></trans-title-group></journal-title-group><issn pub-type="epub">2541-9897</issn><publisher><publisher-name>Scientific Research Institute – Ochapovsky Regional Clinical Hospital No. 1</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">inovmed-103</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL RESEARCH</subject></subj-group></article-categories><title-group><article-title>УСПЕШНАЯ АСПИРАЦИЯ ТРОМБОТИЧЕСКИХ МАСС ИЗ ПРОСВЕТА ЛЕВОЙ ВНУТРЕННЕЙ СОННОЙ АРТЕРИИ С ПРИМЕНЕНИЕМ УСТРОЙСТВА ПРОКСИМАЛЬНОЙ ПРОТИВОЭМБОЛИЧЕСКОЙ ЗАЩИТЫ В УСЛОВИЯХ ПРОВЕДЕНИЯ ТРОМБОЛИТИЧЕСКОЙ ТЕРАПИИ</article-title><trans-title-group xml:lang="en"><trans-title>SUCCESSFUL ASPIRATION OF THROMBOTIC MASSES OUT OF THE LEFT INTERNAL CAROTID ARTERY LUMEN USING A PROXIMAL EMBOLIC PROTECTION DEVICE IN THE CONDITIONS OF THROMBOLYTIC THERAPY PERFORMANCE</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Некрасов</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Nekrasov</surname><given-names>A. S.</given-names></name></name-alternatives><email xlink:type="simple">alexandr_nekrasov1984@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Белый</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Beliy</surname><given-names>A. I.</given-names></name></name-alternatives><email xlink:type="simple">kkb1@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Волколуп</surname><given-names>О. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Volkolup</surname><given-names>O. S.</given-names></name></name-alternatives><email xlink:type="simple">kkb1@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тупикин</surname><given-names>Р. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Tupikin</surname><given-names>P. A.</given-names></name></name-alternatives><email xlink:type="simple">kkb1@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Научно-исследовательский институт – Краевая клиническая больница № 1 им. проф. С.В. Очаповского Министерства здравоохранения Краснодарского края</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Scientific Research Institute – Ochapovsky Regional Clinical Hospital no. 1, The Krasnodar Krai Ministry of Health</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>30</day><month>12</month><year>2017</year></pub-date><volume>8</volume><issue>4</issue><fpage>37</fpage><lpage>41</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Некрасов А.С., Белый А.И., Волколуп О.С., Тупикин Р.А., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Некрасов А.С., Белый А.И., Волколуп О.С., Тупикин Р.А.</copyright-holder><copyright-holder xml:lang="en">Nekrasov A.S., Beliy A.I., Volkolup O.S., Tupikin P.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.innovmedkub.ru/jour/article/view/103">https://www.innovmedkub.ru/jour/article/view/103</self-uri><abstract><p>Комбинированные методики лечения ишемического инсульта все чаще используют в рутинной работе специализированных бригад. Одна из них, основанная на сочетании системной тромболитической терапии и эндоваскулярных методов, характеризуется высоким процентом благоприятных исходов. Однако стоит помнить, что для достижения успеха необходимо уложиться в строго отведенное «терапевтическое окно», в противном случае внутривенное введение тромболитика будет противопоказано, что может существенно повлиять на положительный результат. В данной статье представлено клиническое наблюдение сочетания системной тромболитической терапии и эндоваскулярной механической тромбаспирации с использованием устройства проксимальной противоэмболической защиты при тотальном тромбозе просвета левой внутренней сонной артерии.</p></abstract><trans-abstract xml:lang="en"><p>Combined techniques of treatment for ischemic stroke are even more often included into routine work of specialized teams. One of them based on a combination of systemic thrombolytic therapy and endovascular methods is characterized by a high rate of favorable outcomes. However, it is worth remembering that to achieve success it is necessary to keep within strictly limited therapeutic window, otherwise intravenous administration of a thrombolytic agent will be contraindicated that can significantly affect a positive outcome. Clinical observation for a combination with systemic thrombolytic therapy and endovascular mechanical thromboaspiration with use of the proximal embolic protection device at a total thrombosis of the left internal carotid artery lumen is presented in this article.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>острый ишемический инсульт</kwd><kwd>тромбаспирация</kwd><kwd>тромболитическая терапия</kwd><kwd>комбинированная терапия</kwd><kwd>тромболизис</kwd></kwd-group><kwd-group xml:lang="en"><kwd>acute ischemic stroke</kwd><kwd>thromboaspiration</kwd><kwd>thrombolytic therapy</kwd><kwd>combined modality therapy</kwd><kwd>thrombolysis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Gorelick P.B. Burden of stroke and risk factors. In: Bomstein N.M. (ed). Stroke: practical guide for clinicians. 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