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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">inovmed</journal-id><journal-title-group><journal-title xml:lang="ru">Инновационная медицина Кубани</journal-title><trans-title-group xml:lang="en"><trans-title>Innovative Medicine of Kuban</trans-title></trans-title-group></journal-title-group><issn pub-type="epub">2541-9897</issn><publisher><publisher-name>Scientific Research Institute – Ochapovsky Regional Clinical Hospital No. 1</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.35401/2541-9897-2025-10-1-86-92</article-id><article-id custom-type="elpub" pub-id-type="custom">inovmed-1070</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>СЛУЧАИ ИЗ КЛИНИЧЕСКОЙ ПРАКТИКИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CASE REPORTS</subject></subj-group></article-categories><title-group><article-title>Клиника острого аппендицита при агенезии червеобразного отростка</article-title><trans-title-group xml:lang="en"><trans-title>Clinical Presentation of Acute Appendicitis in Patients With Agenesis of the Vermiform Appendix</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8215-7519</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Андреев</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Andreev</surname><given-names>Alexander A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Андреев Александр Алексеевич, д. м. н., профессор кафедры общей и амбулаторной хирургии</p><p>394036, Воронеж, ул. Студенческая, 10</p></bio><bio xml:lang="en"><p>Alexander A. Andreev, Dr. Sci. (Med.), Professor at the Department of General and Outpatient Surgery</p><p>ulitsa Studencheskaya 10, Voronezh, 394036</p></bio><email xlink:type="simple">aglukhov@vrngmu.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9675-7611</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Глухов</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Glukhov</surname><given-names>Alexander A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Глухов Александр Анатольевич, д. м. н., заведующий кафедрой общей и амбулаторной хирургии</p><p>394036, Воронеж, ул. Студенческая, 10</p></bio><bio xml:lang="en"><p>Alexander A. Glukhov, Dr. Sci. (Med.), Head of the Department of General and Outpatient Surgery</p><p>ulitsa Studencheskaya 10, Voronezh, 394036</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0007-7360-7814</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Горлунов</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gorlunov</surname><given-names>Alexander V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Горлунов Александр Васильевич, к. м. н., заместитель главного врача по хирургической помощи</p><p>Воронеж</p></bio><bio xml:lang="en"><p>Alexander V. Gorlunov, Cand. Sci. (Med.), Deputy Chief Physician for Surgical Care</p><p>Voronezh</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3307-1425</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лаптиёва</surname><given-names>А. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Laptiyova</surname><given-names>Anastasia Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лаптиёва Анастасия Юрьевна, ассистент кафедры общей и амбулаторной хирургии</p><p>Воронеж</p></bio><bio xml:lang="en"><p>Anastasia Yu. Laptiyova, Assistant Professor at the Department of General and Outpatient Surgery</p><p>ulitsa Studencheskaya 10, Voronezh, 394036</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3656-5954</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Остроушко</surname><given-names>А. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Ostroushko</surname><given-names>Anton P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Остроушко Антон Петрович, к. м. н., доцент кафедры общей и амбулаторной хирургии</p><p>394036, Воронеж, ул. Студенческая, 10</p></bio><bio xml:lang="en"><p>Anton P. Ostroushko, Cand. Sci. (Med.), Associate Professor at the Department of General and Outpatient Surgery</p><p>ulitsa Studencheskaya 10, Voronezh, 394036</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Воронежский государственный медицинский университет им. Н.Н. Бурденко</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Voronezh State Medical University named after N.N. Burdenko</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Воронежская городская клиническая больница скорой медицинской помощи № 10</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Voronezh City Clinical Hospital of Emergency Medical Care No. 10</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>30</day><month>03</month><year>2025</year></pub-date><volume>10</volume><issue>1</issue><fpage>86</fpage><lpage>92</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Андреев А.А., Глухов А.А., Горлунов А.В., Лаптиёва А.Ю., Остроушко А.П., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Андреев А.А., Глухов А.А., Горлунов А.В., Лаптиёва А.Ю., Остроушко А.П.</copyright-holder><copyright-holder xml:lang="en">Andreev A.A., Glukhov A.A., Gorlunov A.V., Laptiyova A.Y., Ostroushko A.P.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.innovmedkub.ru/jour/article/view/1070">https://www.innovmedkub.ru/jour/article/view/1070</self-uri><abstract><p>В статье проанализированы 10 случаев агенезии червеобразного отростка, при которых наблюдалась клиническая картина острого аппендицита. Учитывая, что по данным литературы, данная патология встречается на 1 из 100 тыс. оперативных вмешательств по поводу острого аппендицита, можно предположить, что данное количество наблюдений было сделано на основании анализа результатов миллиона операций.</p><p>В статье приводятся данные клинической, в том числе интраоперационной, лабораторной и инструментальной диагностики патологии, представлены рекомендации по выявлению агенезии червеобразного отростка, лечению абдоминального синдрома при данной патологии.</p></abstract><trans-abstract xml:lang="en"><p>This article analyzes 10 cases of agenesis of the vermiform appendix with clinical presentation of acute appendicitis. Given that this pathology occurs in 1 of 100000 surgical interventions for acute appendicitis according to the literature, it can be assumed that this number of observations was based on the analysis of the results of 1 million interventions.</p><p>The article reports clinical (including intraoperative), laboratory, and imaging findings and gives recommendations for detection of agenesis of the vermiform appendix and treatment of abdominal pain syndrome.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>острый аппендицит</kwd><kwd>агенезия аппендикса</kwd></kwd-group><kwd-group xml:lang="en"><kwd>acute appendicitis</kwd><kwd>agenesis of the vermiform appendix</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Hammood ZD, Salih AM, Mahal LA, Yas YT, Ghaleb HA, Kakamad FH. Agenesis of vermiform appendix; a case report with literature review. Int J Surg Case Rep. 2021;87:106364. PMID: 34562720. PMCID: PMC8473660. https://doi.org/10.1016/j.ijscr.2021.106364</mixed-citation><mixed-citation xml:lang="en">Hammood ZD, SalihAM, Mahal LA, YasYT, Ghaleb HA, Kakamad FH. Agenesis of vermiform appendix; a case report with literature review. Int J Surg Case Rep. 2021;87:106364. PMID: 34562720. PMCID: PMC8473660. https://doi.org/10.1016/j.ijscr.2021.106364</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Ghali MS, Saleem N, Khalaf MH, et al. Congenital absence of appendix: a rare condition that could result in severe complicationsa review of literature. J Surg Case Rep. 2023;2023(12):rjad661. PMID: 38111487. PMCID: PMC10725790. https://doi.org/10.1093/jscr/rjad661</mixed-citation><mixed-citation xml:lang="en">Ghali MS, Saleem N, Khalaf MH, et al. Congenital absence of appendix: a rare condition that could result in severe complicationsa review of literature. J Surg Case Rep. 2023;2023(12):rjad661. PMID: 38111487. PMCID: PMC10725790. https://doi.org/10.1093/jscr/rjad661</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Salim A, Moazzam Z, Ashraf A, Dogar SA, Qazi SH. Congenital absence of the appendix in a child with malrotation. Journal of Pediatric Surgery Case Reports. 2020;60:101530. https://doi.org/10.1016/j.epsc.2020.101530</mixed-citation><mixed-citation xml:lang="en">Salim A, Moazzam Z, Ashraf A, Dogar SA, Qazi SH. Congenital absence of the appendix in a child with malrotation. Journal of Pediatric Surgery Case Reports. 2020;60:101530. https://doi.org/10.1016/j.epsc.2020.101530</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Yohannes B, Abebe K. Appendiceal Agenesis: a very rare intraoperative diagnosis - a case report. Int Med Case Rep J. 2021;14:233–236. PMID: 33859503. PMCID: PMC8043782. https://doi.org/10.2147/IMCRJ.S309192</mixed-citation><mixed-citation xml:lang="en">Yohannes B, Abebe K. Appendiceal Agenesis: a very rare intraoperative diagnosis - a case report. Int Med Case Rep J. 2021;14:233–236. PMID: 33859503. PMCID: PMC8043782. https://doi.org/10.2147/IMCRJ.S309192</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Elias EG, Hults R. Congenital absence of vermiform appendix. Arch Surg. 1967;95(2):257–258. PMID: 16097296. https://doi.org/10.1001/archsurg.1967.01330140095022</mixed-citation><mixed-citation xml:lang="en">Elias EG, Hults R. Congenital absence of vermiform appendix. Arch Surg. 1967;95(2):257–258. PMID: 16097296. https://doi.org/10.1001/archsurg.1967.01330140095022</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Chèvre F, Gillet M, Vuilleumier H. Agenesis of the vermiform appendix. Surg Laparosc Endosc Percutan Tech. 2000;10(2):110– 112. PMID: 10789585.</mixed-citation><mixed-citation xml:lang="en">Chèvre F, Gillet M, Vuilleumier H. Agenesis of the vermiform appendix. Surg Laparosc Endosc Percutan Tech. 2000;10(2):110– 112. PMID: 10789585.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Shah TA. A 25-year-old male with appendicular agenesis: A case report and literature review. J Taibah Univ Med Sci. 2016;12(1):75–77. PMID: 31435216. PMCID: PMC6694978. https://doi.org/10.1016/j.jtumed.2016.02.003</mixed-citation><mixed-citation xml:lang="en">Shah TA. A 25-year-old male with appendicular agenesis: A case report and literature review. J Taibah Univ Med Sci. 2016;12(1):75–77. PMID: 31435216. PMCID: PMC6694978. https://doi.org/10.1016/j.jtumed.2016.02.003</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Tripathy BB. Congenital absence of appendix: a surgeon’s dilemma during surgery for acute appendicitis. J Indian Assoc Pediatr Surg. 2016;21(4):199–201. PMID: 27695217. PMCID: PMC4980886. https://doi.org/10.4103/0971-9261.186555</mixed-citation><mixed-citation xml:lang="en">Tripathy BB. Congenital absence of appendix: a surgeon’s dilemma during surgery for acute appendicitis. J Indian Assoc Pediatr Surg. 2016;21(4):199–201. PMID: 27695217. PMCID: PMC4980886. https://doi.org/10.4103/0971-9261.186555</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Giron F, Rey Chaves CE, Rodríguez ML, Conde D, Venegas D, Arango A. Appendicular agenesis as an unusual intraoperative finding in acute abdomen: Case report and literature review. Int J Surg Case Rep. 2022;90:106740. PMID: 34974355. PMCID: PMC8728466. https://doi.org/10.1016/j.ijscr.2021.106740</mixed-citation><mixed-citation xml:lang="en">Giron F, Rey Chaves CE, Rodríguez ML, Conde D, Venegas D, Arango A. Appendicular agenesis as an unusual intraoperative finding in acute abdomen: Case report and literature review. Int J Surg Case Rep. 2022;90:106740. PMID: 34974355. PMCID: PMC8728466. https://doi.org/10.1016/j.ijscr.2021.106740</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Савастюк А.Е., Давыдова Л.А. Морфологические и топографические особенности червеобразного отростка у детей. Молодой ученый. 2021;(44):40–46. Savastsiuk AE, Davydova LA. Morphological features of the vermiform appendix in children. Molodoi uchenyi. 2021;(44):40– 46. (In Russ.).</mixed-citation><mixed-citation xml:lang="en">Савастюк А.Е., Давыдова Л.А. Морфологические и топографические особенности червеобразного отростка у детей. Молодой ученый. 2021;(44):40–46. Savastsiuk AE, Davydova LA. Morphological features of the vermiform appendix in children. Molodoi uchenyi. 2021;(44):40– 46. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Morgagni G, Lancisi GM, Volpi GB. Adversaria anatomica omnia (Quorum tria posteriora nunc primùm prodeunt) Novis pluribus aereis tabulis, &amp; universali accuratissimo indice ornata. Opus nunc vere absolutum, inventis, &amp; innumeris observationibus, ac monitis refertum, quibus universa humani corporis anatome, &amp; ... res medica, &amp; chirurgica admodum illustrantur. 1719. (In Latin).</mixed-citation><mixed-citation xml:lang="en">Morgagni G, Lancisi GM, Volpi GB. Adversaria anatomica omnia (Quorum tria posteriora nunc primùm prodeunt) Novis pluribus aereis tabulis, &amp; universali accuratissimo indice ornata. Opus nunc vere absolutum, inventis, &amp; innumeris observationibus, ac monitis refertum, quibus universa humani corporis anatome, &amp; ... res medica, &amp; chirurgica admodum illustrantur. 1719. (In Latin).</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Sedik A, Al-Dawoodi T, Elhoushy S. Appendicular agenesis: a case report. International Surgery Journal. 2018;5(3): 1121–1123.</mixed-citation><mixed-citation xml:lang="en">Sedik A, Al-Dawoodi T, Elhoushy S. Appendicular agenesis: a case report. International Surgery Journal. 2018;5(3): 1121–1123.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Глухов А.А., Андреев А.А., Горлунов А.В. и др. Клинический случай отсутствия червеобразного отростка. Вестник экспериментальной и клинической хирургии. 2022;15(2):162– 164. https://doi.org/10.18499/2070-478x-2022-15-2-162-164</mixed-citation><mixed-citation xml:lang="en">Глухов А.А., Андреев А.А., Горлунов А.В. и др. Клинический случай отсутствия червеобразного отростка. Вестник экспериментальной и клинической хирургии. 2022;15(2):162– 164. https://doi.org/10.18499/2070-478x-2022-15-2-162-164 Glukhov AA, Andreev AA, Gorlunov AV, et al. Clinical case of absence of the appendix. Journal of Experimental and Clinical Surgery. 2022;15(2):162–164. (In Russ.). https://doi.org/10.18499/2070-478x-2022-15-2-162-164</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Vincent MV, Doyle A, Bernstein S, Jackman S. Absence of the appendix discovered during childhood. Springerplus. 2014;3:522. PMID: 25279313. PMCID: PMC4166596. https://doi.org/10.1186/2193-1801-3-522</mixed-citation><mixed-citation xml:lang="en">Vincent MV, Doyle A, Bernstein S, Jackman S. Absence of the appendix discovered during childhood. Springerplus. 2014;3:522. PMID: 25279313. PMCID: PMC4166596. https://doi. org/10.1186/2193-1801-3-522</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Zetina-Mejía CA, Alvarez-Cosío JE, Quillo-Olvera J. Congenital absence of the cecal appendix. Case report. Cir Cir. 2009;77(5):407–410. PMID: 19944032.</mixed-citation><mixed-citation xml:lang="en">Zetina-Mejía CA, Alvarez-Cosío JE, Quillo-Olvera J. Congenital absence of the cecal appendix. Case report. Cir Cir. 2009;77(5):407–410. PMID: 19944032.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Nissler V, Fleischmann J, Hümmer HP, Knorr C. Agenesis of the vermiform appendix. J Pediatr Surg. 2012;47(6):1302–1303. PMID: 22703811. https://doi.org/10.1016/j.jpedsurg.2012.03.050</mixed-citation><mixed-citation xml:lang="en">Nissler V, Fleischmann J, Hümmer HP, Knorr C. Agenesis of the vermiform appendix. J Pediatr Surg. 2012;47(6):1302–1303. PMID: 22703811. https://doi.org/10.1016/j.jpedsurg.2012.03.050</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Ghali MS, Saleem N, Khalaf MH, et al. Congenital absence of appendix: a rare condition that could result in severe complications-a review of literature. J Surg Case Rep. 2023;2023(12):rjad661. PMID: 38111487. PMCID: PMC10725790. https://doi.org/10.1093/jscr/rjad661.</mixed-citation><mixed-citation xml:lang="en">Ghali MS, Saleem N, Khalaf MH, et al. Congenital absence of appendix: a rare condition that could result in severe complications-a review of literature. J Surg Case Rep. 2023;2023(12):rjad661. PMID: 38111487. PMCID: PMC10725790. https://doi.org/10.1093/jscr/rjad661.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
