inovmedИнновационная медицина КубаниInnovative Medicine of Kuban2541-9897Scientific Research Institute – Ochapovsky Regional Clinical Hospital No. 110.35401/2541-9897-2025-10-2-7-15inovmed-1181Research ArticleТЕХНОЛОГИЧЕСКИЕ ДОСТИЖЕНИЯ В МЕДИЦИНЕTECHNOLOGICAL ACHIEVEMENTS IN MEDICINEНанотехнологии и системы доставки лекарственных средств для заживления ран и уменьшения рубцовNanotechnology and Drug Delivery Systems in Wound Healing and Scar Reductionhttps://orcid.org/0000-0003-0085-3284ЭскандарК.EskandarK.

Эскандар Киролос - MBBCh, MA, медицинский работник, факультет медицины и хирургии.

Хелуан, мухафаза Каир 4037120

Kirolos Eskandar - MBBCh, MA, Medical Professional, Faculty of Medicine and Surgery, Helwan University.

Helwan, Cairo Governorate 4037120

kiroloss.eskandar@gmail.comХелуанский университетЕгипетHelwan UniversityEgypt202530062025102715Copyright © Эскандар К., 20252025Эскандар К.Eskandar K.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.innovmedkub.ru/jour/article/view/1181

Нанотехнологии – инновационный подход в заживлении ран и уменьшении рубцов, предлагающий системы точной, адресной и эффективной доставки лекарств. В данном обзоре освещаются последние достижения в области нанотехнологий (наночастицы, нановолокна, гидрогели и наноэмульсии), имеющие превосходство над традиционными методами лечения. Данные инновационные разработки повышают антимикробную активность, способствуют ангиогенезу, модулируют воспаление и с прецизионной точностью доставляют терапевтические агенты. Интеграция нанотехнологий с препаратами для уменьшения рубцов открывает революционные возможности для ремоделирования коллагена и подавления фиброза, улучшая как функциональные, так и эстетические результаты лечения. Кроме того, «умные» наноматериалы с биосенсорами позволяют в режиме реального времени отслеживать состояние раны и корректировать лечение. Несмотря на многообещающие результаты, остаются нерешенными вопросы, связанные с биосовместимостью, цитотоксичностью и одобрением регулирующих органов.

В данном обзоре подчеркивается огромное влияние нанотехнологий на прогресс в лечении ран и дается представление о направлениях дальнейших исследований, а именно о персонализированной медицине и системах, интегрированных с искусственным интеллектом, для оптимизации результатов лечения.

Nanotechnology has emerged as a revolutionary approach in wound healing and scar reduction, offering precise, targeted, and efficient drug delivery systems. This review highlights recent advances in nanotechnology-based solutions, including nanoparticles, nanofibers, hydrogels, and nanoemulsions that address limitations of conventional therapies. These innovations enhance antimicrobial activity, promote angiogenesis, modulate inflammation, and deliver therapeutic agents with remarkable precision. The integration of nanotechnology with scar-reducing agents has transformative potential for collagen remodeling and fibrosis inhibition, improving both functional and esthetic outcomes. Furthermore, smart nanomaterials with biosensing capabilities enable real-time wound monitoring and dynamic treatment adjustments. While these advances are promising, challenges related to biocompatibility, cytotoxicity, and regulatory approval remain critical to address.

This review emphasizes the profound impact of nanotechnology in revolutionizing wound care and provides insights into future directions, including personalized therapies and artificial intelligence-integrated systems for optimized outcomes.

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The authors declare that there are no conflicts of interest present.