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<article article-type="review-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">inovmed</journal-id><journal-title-group><journal-title xml:lang="ru">Инновационная медицина Кубани</journal-title><trans-title-group xml:lang="en"><trans-title>Innovative Medicine of Kuban</trans-title></trans-title-group></journal-title-group><issn pub-type="epub">2541-9897</issn><publisher><publisher-name>Scientific Research Institute – Ochapovsky Regional Clinical Hospital No. 1</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.35401/2541-9897-2025-10-3-99-105</article-id><article-id custom-type="elpub" pub-id-type="custom">inovmed-1279</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Спинальная анестезия у пациентов с морбидным ожирением: риски, преимущества и перспективы</article-title><trans-title-group xml:lang="en"><trans-title>Spinal Anesthesia in Morbidly Obese Patients: Risks, Benefits, and Future Perspectives</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6987-7519</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Нематуллоев</surname><given-names>Т. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Nematulloev</surname><given-names>T. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Нематуллоев Тухтасин Комилжонович, ассистент кафедры анестезиологии, реанимации и неотложной медицины</p><p>140100, Самарканд, ул. Амира Темура 18</p></bio><bio xml:lang="en"><p>Tukhtasin K. Nematulloev, Assistant of the Department of Anesthesiology, Resuscitation, and Emergency Medicine</p><p>18 Amir Temur, Samarkand, 140100</p></bio><email xlink:type="simple">tukhtasinnematulloev@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8596-1430</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Матлубов</surname><given-names>М. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Matlubov</surname><given-names>M. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Матлубов Мансур Муратович, д. м. н., профессор, заведующий кафедрой анестезиологии, реанимации и неотложной медицины</p><p>140100, Самарканд, ул. Амира Темура 18</p></bio><bio xml:lang="en"><p>Mansur M. Matlubov, Dr. Sci. (Med.), Professor, Head of the Department of Anesthesiology, Resuscitation, and Emergency Medicine</p><p>18 Amir Temur, Samarkand, 140100</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Самаркандский государственный медицинский университет</institution><country>Узбекистан</country></aff><aff xml:lang="en"><institution>Samarkand State Medical University</institution><country>Uzbekistan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>30</day><month>09</month><year>2025</year></pub-date><volume>10</volume><issue>3</issue><fpage>99</fpage><lpage>105</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Нематуллоев Т.К., Матлубов М.М., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Нематуллоев Т.К., Матлубов М.М.</copyright-holder><copyright-holder xml:lang="en">Nematulloev T.K., Matlubov M.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.innovmedkub.ru/jour/article/view/1279">https://www.innovmedkub.ru/jour/article/view/1279</self-uri><abstract><p>Актуальность: Морбидное ожирение сопровождается особыми физиологическими сдвигами, повышающими вероятность возникновения осложнений в пред-, интра- и постоперационном периодах. Одним из многообещающих методов снижения рисков, ассоциированных с общим наркозом, является спинальная анестезия. Однако вопросы безопасности и эффективности данного метода конкретно у пациентов с морбидным ожирением нуждаются в дополнительном изучении и научном обосновании.Цель: Оценить безопасность, эффективность и потенциальные преимущества спинальной анестезии у пациентов с морбидным ожирением, а также разработать рекомендации для снижения рисков.Материалы и методы: Проведен анализ 12 исследований (2013–2023 гг.), включавших более 1 500 пациентов с морбидным ожирением. Были проанализированы клинические результаты, частота осложнений и удовлетворенность пациентов. Использованы данные рандомизированных исследований, метаанализов и крупных когортных наблюдений.Результаты: Спинальная анестезия у пациентов с морбидным ожирением ассоциируется с меньшим количеством дыхательных осложнений (отношение шансов 0,4; 95% ДИ 0,3–0,6), сниженной потребностью в опиоидах и более коротким сроком восстановления по сравнению с общей анестезией. Однако наблюдаются технические трудности из-за анатомических особенностей, повышенный риск гипотензии (15%) и умеренно повышенная частота постпункционной головной боли (3%).Заключение: Спинальная анестезия может быть безопасным и эффективным методом для пациентов с морбидным ожирением при условии тщательного планирования и мониторинга.</p></abstract><trans-abstract xml:lang="en"><p>Background: Morbid obesity is associated with unique physiological alterations that elevate the risk of perioperative complications. Spinal anesthesia represents a promising approach that may reduce the risks related to general anesthesia; however, its safety and efficacy in morbidly obese patients require further investigation.Objective: To evaluate the safety, efficacy, and potential benefits of spinal anesthesia in morbidly obese patients and to develop recommendations for minimizing associated risks.Materials and Methods: An analysis of 12 studies (2013–2023) involving over 1,500 morbidly obese patients was conducted. Clinical outcomes, complication rates, and patient satisfaction were evaluated. Data from randomized controlled trials, meta-analyses, and large cohort studies were utilized.Results: Spinal anesthesia in morbidly obese patients is associated with fewer respiratory complications (odds ratio 0.4; 95% CI 0.3–0.6), reduced opioid requirements, and shorter recovery time compared to general anesthesia. However, technical challenges due to anatomical characteristics, an increased risk of hypotension (15%), and a moderately higher incidence of post-dural puncture headache (3%) were observed.Conclusions: Spinal anesthesia may be a safe and effective option for morbidly obese patients when thorough planning and monitoring are implemented.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>морбидное ожирение</kwd><kwd>спинальная анестезия</kwd><kwd>периоперационная безопасность</kwd><kwd>дыхательные осложнения</kwd><kwd>гипотензия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>morbid obesity</kwd><kwd>spinal anesthesia</kwd><kwd>perioperative safety</kwd><kwd>respiratory complications</kwd><kwd>hypotension</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Lim Y, Haq N, Boster J. Obesity and Comorbid Conditions. In: StatPearls. Treasure Island (FL): StatPearls. 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