inovmedИнновационная медицина КубаниInnovative Medicine of Kuban2541-9897Scientific Research Institute – Ochapovsky Regional Clinical Hospital No. 1inovmed-143Research ArticleСЛУЧАИ ИЗ ПРАКТИКИCASE REPORTSКЛИНИЧЕСКИЙ СЛУЧАЙ ПЕРВИЧНОГО ГИПЕРПАРАТИРЕОЗА С МНОЖЕСТВЕННЫМИ АДЕНОМАМИCLINICAL CASE OF INITIAL HYPERPARATHYROIDISM WITH MULTIPLE ADENOMASРомашА. В.RomashA. V.doctoranna79@gmail.comТерманЕ. А.TermanE. A.terman@mail.ruНаучно-исследовательский институт – Краевая клиническая больница № 1 им. проф. С.В. Очаповского Министерства здравоохранения Краснодарского краяРоссияScientific Research Institute – Ochapovsky Regional Clinical Hospital no. 1, The Krasnodar Krai Ministry of HealthRussian Federation201830062018025761Copyright © Ромаш А.В., Терман Е.А., 20182018Ромаш А.В., Терман Е.А.Romash A.V., Terman E.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.innovmedkub.ru/jour/article/view/143

В статье приведен интересный клинический случай первичного гиперпаратиреоза с множественными аденомами паращитовидной железы. Показана целесообразность совместного применения инструментальных визуализирующих методов обследования. Отмечена роль сцинтиграфии в качестве метода предоперационной визуализации измененных паращитовидных желез, которая значительно улучшает результаты хирургического лечения и сокращает время операции.

In the present article we described an interesting clinical case with multiple adenomas of parathyroid gland. We demonstrated proper combined application of visualising methods. Scintigraphy as a method of preoperative visualisation is defined as improving surgical results and reducing operative time.

первичный гиперпаратиреозаденома паращитовидных желездефицит витамина Дкоморбидная патологияinitial hyperparathyroidismparathyroid gland adenomahypovitaminosis Dcomorbide pathologyReferencesMorris A.D., Boyle D. IR., MacAlpine R., Emslie Smith А., Jung R.T., Newton R.W., MacDonald T.M. The diabetes audit and research in Tayside Scotland (DARTS) study: electronic record linkage to create a diabetes register. Br Med. J. 1997; 315: 524-528.Morris A.D., Boyle D. IR., MacAlpine R., Emslie Smith А., Jung R.T., Newton R.W., MacDonald T.M. The diabetes audit and research in Tayside Scotland (DARTS) study: electronic record linkage to create a diabetes register. Br Med. J. 1997; 315: 524-528.Flynn R.W., MacDonald T.M., Jung R.T., Morris A.D., Leese G.P. Mortality and vascular outcomes in patients treated for thyroid dysfunction. J. Clin. Endocrinol. Metab. 2006; 91: 2159-2164.Flynn R.W., MacDonald T.M., Jung R.T., Morris A.D., Leese G.P. Mortality and vascular outcomes in patients treated for thyroid dysfunction. J. Clin. Endocrinol. Metab. 2006; 91: 2159-2164.Diaz Soto G., Julian M.T., Puig Dominigo M. Normocalcemic primary hyperparathyroidism: a newly emerging disease needing therapeutic intervention. Hormones (Athens). 2012; 11: 390-6.Diaz Soto G., Julian M.T., Puig Dominigo M. Normocalcemic primary hyperparathyroidism: a newly emerging disease needing therapeutic intervention. Hormones (Athens). 2012; 11: 390-6.Kaplan E.L., Yashiro T., Salti G. Primary hyperparathyroidism in the 1990s. Choice of surgical procedures for this disease. Ann. Surg. 1992; 4(215): 300-317.Kaplan E.L., Yashiro T., Salti G. Primary hyperparathyroidism in the 1990s. Choice of surgical procedures for this disease. Ann. Surg. 1992; 4(215): 300-317.Marcocci C., Cetani F. Clinical practice. Primary hyperparathyroidism. N Engl J Med. 2011; 365: 2389-2397.Marcocci C., Cetani F. Clinical practice. Primary hyperparathyroidism. N Engl J Med. 2011; 365: 2389-2397.Coakley A.J., Kettle A.G., Wells C.P., O’Doherty M.J., Collins R.E. 99Tcm sestamibi - a new agent for parathyroid imaging. Nucl. Med. Commun. 1989; 10: 791-794.Coakley A.J., Kettle A.G., Wells C.P., O’Doherty M.J., Collins R.E. 99Tcm sestamibi - a new agent for parathyroid imaging. Nucl. Med. Commun. 1989; 10: 791-794.Johnson N.A., Tublin M.E., Ogilvie J.B. Parathyroid imaging: Technique and role in the preoperative evaluation of primary hyperparathyroidism. AJR. 2007; 188: 1706-1715.Johnson N.A., Tublin M.E., Ogilvie J.B. Parathyroid imaging: Technique and role in the preoperative evaluation of primary hyperparathyroidism. AJR. 2007; 188: 1706-1715.Randolph G.W. Surgery of the thyroid and parathyroid glands. Philadelphia: Elsevier Science (USA). 2003. P. 620.Randolph G.W. Surgery of the thyroid and parathyroid glands. Philadelphia: Elsevier Science (USA). 2003. P. 620.Allendorf J., Kim L., Chabot J., Digiorgi М, Spanknebel К, Logerfo Р. The impact of Sestamibi scanning on the outcome of parathyroid surgery. J. Clin. Endocrinol. Metab. 2003; 88: 3015-3018.Allendorf J., Kim L., Chabot J., Digiorgi М, Spanknebel К, Logerfo Р. The impact of Sestamibi scanning on the outcome of parathyroid surgery. J. Clin. Endocrinol. Metab. 2003; 88: 3015-3018.Lumachi F., Zucchetta Р., Marzola М.С., Boccagni Р., Angelini F., Bui F., D’Amico D.F., Favia1 G. Advantages of combined techneticum-99m-sesta-mibi scintigraphyand high-resolution ultrasonography in parathyroid localization: comparative study in 91 patients with primary hyperparathyroidism. European Journal of Endocrinology. 2000; 143: 755-760.Lumachi F., Zucchetta Р., Marzola М.С., Boccagni Р., Angelini F., Bui F., D’Amico D.F., Favia1 G. Advantages of combined techneticum-99m-sesta-mibi scintigraphyand high-resolution ultrasonography in parathyroid localization: comparative study in 91 patients with primary hyperparathyroidism. European Journal of Endocrinology. 2000; 143: 755-760.Haciyanli M., Lal G., Morita E., Duh Q.Y., Kebebew E., Clark O.H. Accuracy of preoperative localization studies and intraoperative parathyroid hormone assay in patients with primary hyperparathyroidism and double adenoma. J. Am.Coll. Surg. 2003; 197: 739-746.Haciyanli M., Lal G., Morita E., Duh Q.Y., Kebebew E., Clark O.H. Accuracy of preoperative localization studies and intraoperative parathyroid hormone assay in patients with primary hyperparathyroidism and double adenoma. J. Am.Coll. Surg. 2003; 197: 739-746.Johnson N.A., Tublin M.E., Ogilvie J.B. Parathyroid imaging: Technique and role in the preoperative evaluation of primary hyperparathyroidism. AJR. 2007; 188: 1706-1715.Johnson N.A., Tublin M.E., Ogilvie J.B. Parathyroid imaging: Technique and role in the preoperative evaluation of primary hyperparathyroidism. AJR. 2007; 188: 1706-1715.Fuster D., Ybarra J., Ortin J., Torregrosa J.V., Gilabert R., Setoain X. et al. Role of pre-operative imaging using (99m)Tc-MIBI and neck ultrasound in patients with secondary hyperparathyroidism who are candidates for subtotal parathyroidectomy. Eur. J. Nucl. Med. Mol. Imaging. 2006; 33: 467-473.Fuster D., Ybarra J., Ortin J., Torregrosa J.V., Gilabert R., Setoain X. et al. Role of pre-operative imaging using (99m)Tc-MIBI and neck ultrasound in patients with secondary hyperparathyroidism who are candidates for subtotal parathyroidectomy. Eur. J. Nucl. Med. Mol. Imaging. 2006; 33: 467-473.Kasai E.T., da Silva J.W., Mandarim de Lacerda C.A., Boasquevisque E. Parathyroid glands: combination of sestamibi-(99m) Tc scintigraphy and ultrasonography for demonstration of hyperplasic parathyroid glands. Rev. Esp. Med. Nucl. 2008; 27: 8-12.Kasai E.T., da Silva J.W., Mandarim de Lacerda C.A., Boasquevisque E. Parathyroid glands: combination of sestamibi-(99m) Tc scintigraphy and ultrasonography for demonstration of hyperplasic parathyroid glands. Rev. Esp. Med. Nucl. 2008; 27: 8-12.

The authors declare that there are no conflicts of interest present.