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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">inovmed</journal-id><journal-title-group><journal-title xml:lang="ru">Инновационная медицина Кубани</journal-title><trans-title-group xml:lang="en"><trans-title>Innovative Medicine of Kuban</trans-title></trans-title-group></journal-title-group><issn pub-type="epub">2541-9897</issn><publisher><publisher-name>Scientific Research Institute – Ochapovsky Regional Clinical Hospital No. 1</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.35401/2500-0268-2020-18-2-6-14</article-id><article-id custom-type="elpub" pub-id-type="custom">inovmed-269</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Послеоперационный делирий у пациентов пожилого возраста после торакальных операций</article-title><trans-title-group xml:lang="en"><trans-title>Postoperative delirium in elderly patients after thoracic surgery</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1427-4032</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бушуев</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Bushuev</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бушуев Александр Сергеевич, врач-ординатор отделения анестезиологии и реанимации № 1</p></bio><bio xml:lang="en"><p>Alexandr S. Bushuev, Resident Physician of Anaesthesiology and Reanimation Department no. 1</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5147-5637</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жихарев</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhikharev</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Жихарев Василий Александрович, к. м. н., старший ординатор отделения анестезиологии и реанимации № 1</p><p>350086, Краснодар, ул. 1 Мая, 167</p></bio><bio xml:lang="en"><p>Vasiliy A. Zhikharev, Cand. of Sci. (Med.), Senior Resident of Anaesthesiology and Reanimation Department no. 1</p><p>167, 1st May str., Krasnodar, 350086</p></bio><email xlink:type="simple">Vasilii290873@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0572-1395</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Порханов</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Porhanov</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Порханов Владимир Алексеевич, академик РАН, д. м. н., профессор, главный врач; заведующий кафедрой онкологии с курсом торакальной хирургии факультета повышения квалификации и профессиональной переподготовки специалистов</p></bio><bio xml:lang="en"><p>Vladimir A. Porhanov, Academician of the Russian Academy of Sciences, Dr. of Sci. (Med.), Professor, Chief Doctor; Head of the Department of Oncology with the Course of Thoracic Surgery, Faculty of Advanced Training and Professional Retraining of Specialists</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3400-8989</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Корячкин</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Koriachkin</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Корячкин Виктор Анатольевич, д. м. н., профессор кафедры анестезиологии, реаниматологии и неотложной педиатрии им. проф. В.И. Гордеева</p></bio><bio xml:lang="en"><p>Viktor A. Koriachkin, Dr. of Sci. (Med.), Professor, Anaesthesiology, Reanimation and Pediatric Emergency Department</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2770-2857</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шолин</surname><given-names>И. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Sholin</surname><given-names>I. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шолин Иван Юрьевич, заведующий отделением анестезиологии и реанимации № 6</p></bio><bio xml:lang="en"><p>Ivan Yu. Sholin, Head of Anaesthesiology and Reanimation Department no. 1</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4191-4496</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Малышев</surname><given-names>Ю. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Malyshev</surname><given-names>Yu. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Малышев Юрий Павлович, д. м. н., профессор кафедры анестезиологии, реаниматологии и трансфузиологии факультета повышения квалификации и профессиональной переподготовки специалистов</p></bio><bio xml:lang="en"><p>Yuriy P. Malyshev, Dr. of Sci. (Med.), Professor, Anaesthesiology, Reanimation and Transfusion Department, Faculty of Advanced Training and Professional Retraining of Specialists</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Научно-исследовательский институт – Краевая клиническая больница № 1 им. проф. С.В. Очаповского Министерства здравоохранения Краснодарского края</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Scientific Research Institute – Ochapovsky Regional Clinical Hospital no. 1</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Научно-исследовательский институт – Краевая клиническая больница № 1 им. проф. С.В. Очаповского Министерства здравоохранения Краснодарского края; Кубанский государственный медицинский университет Министерства здравоохранения РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Scientific Research Institute – Ochapovsky Regional Clinical Hospital no. 1;&#13;
Kuban State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Санкт-Петербургский государственный педиатрический медицинский университет Министерства здравоохранения РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>St. Petersburg State Pediatric Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>30</day><month>06</month><year>2020</year></pub-date><volume>0</volume><issue>2</issue><fpage>6</fpage><lpage>14</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Бушуев А.С., Жихарев В.А., Порханов В.А., Корячкин В.А., Шолин И.Ю., Малышев Ю.П., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Бушуев А.С., Жихарев В.А., Порханов В.А., Корячкин В.А., Шолин И.Ю., Малышев Ю.П.</copyright-holder><copyright-holder xml:lang="en">Bushuev A.S., Zhikharev V.A., Porhanov V.A., Koriachkin V.A., Sholin I.Y., Malyshev Y.P.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.innovmedkub.ru/jour/article/view/269">https://www.innovmedkub.ru/jour/article/view/269</self-uri><abstract><sec><title>Актуальность</title><p>Актуальность. Послеоперационный делирий – одно из наиболее тяжелых и распространенных осложнений после торакальных операций у пациентов пожилого возраста.</p></sec><sec><title>Цель</title><p>Цель. Разработка простого и точного метода прогнозирования развития послеоперационного делирия у больных после торакальных операций.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. Проведено обсервационное когортное исследование 303 пациентов, подвергшихся лобэктомии по поводу онкологических заболеваний. Проанализированы характер анестезии и оперативного вмешательства, особенности волемического статуса и гемодинамические изменения в периоперационном периоде, оценены лабораторные показатели периоперационного периода.</p></sec><sec><title>Результаты</title><p>Результаты. Послеоперационный делирий выявлен у 43 (14,2%) пациентов из 303, включенных в исследование. К немодифицируемым факторам его развития отнесены: возраст, нарушения мозгового кровообращения в анамнезе, алкоголизм, хроническая сердечная недостаточность, более тяжелый физический статус по классификации Американского общества анестезиологов (англ. American Society of Anesthesiologists, ASA); к модифицируемым – длительность однолегочной вентиляции, эпизоды периоперационной гипотонии и гипоксемии, использование опиоидов, интенсивность болевого синдрома в послеоперационном периоде и сниженная кислородтранспортная функция крови. Кроме того, ряд лабораторных показателей (альбумин крови, глюкоза крови, лейкоцитоз), отражающих степень хирургического стресса, также могут быть полезны в прогнозировании.</p></sec><sec><title>Выводы</title><p>Выводы. Составлен прогностический коэффициент с процентом конкордантности 99,9 и Somers' D 0,998. Прогностический коэффициент равен сумме произведений: (–3,5367) × интенсивность боли по 10-балльной визуально-аналоговой шкале через 1 ч. после операции; 2,2037 × уровень альбумина крови на следующее утро после операции; (–4,8151) × уровень глюкозы крови на следующее утро после операции. </p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Background</title><p>Background. Postoperative delirium is one of the most severe and common complications of thoracic surgery in elderly patients.</p></sec><sec><title>Objective</title><p>Objective. To establish a simple and accurate method for predicting the development of postoperative delirium in patients after thoracic surgery.</p></sec><sec><title>Material and Methods</title><p>Material and Methods. We performed an observational cohort study of 303 patients who underwent lobectomy for oncological diseases. The nature of anesthesia and surgical intervention, features of the volume status and hemodynamic changes during the perioperative period were analyzed, laboratory indicators of this period were evaluated.</p></sec><sec><title>Results</title><p>Results. Of 303 patients, 43 (14.2%) developed postoperative delirium. Non-modifiable factors for the development of postoperative delirium included age, history of cerebrovascular accident, alcohol misuse disorder, chronic heart failure, more severe physical status according to the ASA (American Society of Anesthesiologists) Physical Status Classification System. Modifiable factors are the following: the duration of one-lung ventilation, episodes of perioperative hypotension and hypoxemia, the use of opioids, the intensity of the pain syndrome in the postoperative period, and reduced oxygen transport function of the blood. A number of laboratory parameters (blood albumin, blood glucose, leukocytosis), reflecting the degree of surgical stress, may also be useful in postoperative delirium predicting.</p></sec><sec><title>Conclusion</title><p>Conclusion. A prognostic coefficient was compiled with a concordance of 99.9 and Somers' D 0.998. It is equal to the sum of the products: (–3.5367) multiplied by pain intensity on a 10 cm Visual Analogue Scale an hour after surgery; 2.2037 multiplied by the blood albumin level the morning after surgery;    (–4.8151) multiplied by the blood glucose level the morning after surgery. </p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>послеоперационный делирий</kwd><kwd>однолегочная вентиляция</kwd><kwd>гипоксемия</kwd><kwd>болевой синдром</kwd><kwd>гипоальбуминемия</kwd><kwd>гипергликемия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>postoperative delirium</kwd><kwd>one-lung ventilation</kwd><kwd>hypoxemia</kwd><kwd>pain syndrome</kwd><kwd>hypoalbuminemia</kwd><kwd>hyperglycemia</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Florou C, Theofilopoulos D, Tziaferi S, Chania M. 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