inovmedИнновационная медицина КубаниInnovative Medicine of Kuban2541-9897Scientific Research Institute – Ochapovsky Regional Clinical Hospital No. 1inovmed-40Research ArticleОБЗОРЫREVIEWSСОВРЕМЕННЫЕ ПОДХОДЫ К ДИАГНОСТИКЕ И ЛЕЧЕНИЮ ИНВАЗИВНОГО КАНДИДОЗА У РЕЦИПИЕНТОВ ДОНОРСКИХ ОРГАНОВ (ЧАСТЬ II)MODERN APPROACH TO INVASIVE CANDIDIASIS DIAGNOSIS AND TREATMENT IN DONOR ORGAN RECIPIENTS (PART II)БолотоваЕ. В.BolotovaE. V.bolotowa_e@mail.ruШульженкоЛ. В.ShulzhenkoL. V.noemail@neicon.ruПорхановВ. А.PorhanovV. A.noemail@neicon.ruАнтинянА. Э.AntinyanA. E.noemail@neicon.ruБожкоО. В.BozhkoO. V.noemail@neicon.ruСмолинА. А.SmolinA. A.noemail@neicon.ruКубанский государственный медицинский университет Министерства здравоохранения РФ; Научно-исследовательский институт – Краевая клиническая больница № 1 им. проф. С.В. Очаповского Министерства здравоохранения Краснодарского краяРоссияKuban State Medical University, Ministry of Health of the Russian Federation; Scientific Research Institute – Ochapovsky Regional Clinical Hospital no. 1, The Krasnodar Krai Ministry of HealthRussian FederationНаучно-исследовательский институт – Краевая клиническая больница № 1 им. проф. С.В. Очаповского Министерства здравоохранения Краснодарского краяРоссияScientific Research Institute – Ochapovsky Regional Clinical Hospital no. 1, The Krasnodar Krai Ministry of HealthRussian Federation201630122016045460Copyright © Болотова Е.В., Шульженко Л.В., Порханов В.А., Антинян А.Э., Божко О.В., Смолин А.А., 20162016Болотова Е.В., Шульженко Л.В., Порханов В.А., Антинян А.Э., Божко О.В., Смолин А.А.Bolotova E.V., Shulzhenko L.V., Porhanov V.A., Antinyan A.E., Bozhko O.V., Smolin A.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.innovmedkub.ru/jour/article/view/40

У реципиентов донорских органов существенно возрастает риск развития инвазивных грибковых инфекций, большинство из которых обусловлено Candida spp. и Aspergillus spp. Клинические признаки инвазивного кандидоза многообразны, что затрудняет раннюю диагностику. Вместе с тем, несмотря на относительную частоту инвазивных микозов при трансплантации, определенные четкие рекомендации по диагностике, лечению и профилактике инвазивных грибковых инфекций отсутствуют. В большинстве случаев врачам-клиницистам приходится опираться в основном на собственный клинический опыт. В представленном обзоре отражены современные подходы к диагностике и лечению инвазивного кандидоза у реципиентов донорских органов.

In donor organ recipients we observe sufficiently high risk of invasive mycotic infection development and most of them are caused by Candida spp and Aspergillus spp. Clinical evidence of invasive candidiasis are diverse and this fact makes early diagnosis complicated. At the same time, despite relative frequency of invasive mycoses at transplantation, there are no definite recommendations for diagnosis, treatment and prevention of mycotic infections. In most cases physicians should rely on their own clinical experience. In the present study we demonstrated modern approaches to diagnosis and treatment for invasive candidiasis in donor organ recipients.

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The authors declare that there are no conflicts of interest present.