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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">inovmed</journal-id><journal-title-group><journal-title xml:lang="ru">Инновационная медицина Кубани</journal-title><trans-title-group xml:lang="en"><trans-title>Innovative Medicine of Kuban</trans-title></trans-title-group></journal-title-group><issn pub-type="epub">2541-9897</issn><publisher><publisher-name>Scientific Research Institute – Ochapovsky Regional Clinical Hospital No. 1</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.35401/2500-0268-2022-25-1-77-82</article-id><article-id custom-type="elpub" pub-id-type="custom">inovmed-510</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Интраоперационная лучевая терапия в лечении раннего рака молочной железы. От прошлого к будущему</article-title><trans-title-group xml:lang="en"><trans-title>Intraoperative radiation therapy in the treatment of breast cancer. From the past to the future</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7834-7042</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чумаченко</surname><given-names>И. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Chumachenko</surname><given-names>I. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Чумаченко Игорь Сергеевич, врач-онколог онкологического отделения № 8</p><p>350040, Краснодар, ул. Димитрова, 146</p></bio><bio xml:lang="en"><p>Igor S. Chumachenko, Oncologist of the Oncology Department no. 8</p><p>146, Dimitrova str., Krasnodar, 350040</p></bio><email xlink:type="simple">appchumachenko@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8873-8461</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мурашко</surname><given-names>Р. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Murashko</surname><given-names>R. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мурашко Роман Алексеевич, к. м. н., главный врач</p><p>Краснодар</p></bio><bio xml:lang="en"><p>Roman A. Murashko, Cand. Sci. (Med.), Chief Physician</p><p>Krasnodar</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5135-4111</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кешабян</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Keshabyan</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кешабян Артур Арамович, к. м. н., заведующий онкологическим отделением № 8</p><p>Краснодар </p></bio><bio xml:lang="en"><p>Arthur A. Keshabyan, Cand. Sci. (Med.), Head of the Oncology Department no. 8</p><p>Krasnodar</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Клинический онкологический диспансер № 1</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Clinical Oncology Dispensary no. 1</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>30</day><month>03</month><year>2022</year></pub-date><volume>0</volume><issue>1</issue><fpage>77</fpage><lpage>82</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Чумаченко И.С., Мурашко Р.А., Кешабян А.А., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Чумаченко И.С., Мурашко Р.А., Кешабян А.А.</copyright-holder><copyright-holder xml:lang="en">Chumachenko I.S., Murashko R.A., Keshabyan A.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.innovmedkub.ru/jour/article/view/510">https://www.innovmedkub.ru/jour/article/view/510</self-uri><abstract><p>В статье рассматривается опыт применения интраоперационной лучевой терапии в лечении больных раком молочной железы на ранней стадии, а также пути развития данного направления с точки зрения перспектив (улучшения качества лечения, снижения выраженности побочных эффектов, отсутствия влияния на соседние органы) и рисков (вероятности локального рецидивирования) для пациентов.</p></abstract><trans-abstract xml:lang="en"><p>This article discusses the experience of using intraoperative radiation therapy in the treatment of patients with breast cancer, as well as the prospects for the development of this area in terms of benefits (improved therapy effect, reduced severity of side effects, no effect on adjacent organs) and risks (the possibility of local recurrence) for patients.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>рак молочной железы</kwd><kwd>интраоперационная лучевая терапия</kwd><kwd>лучевая терапия</kwd><kwd>парциальное облучение</kwd></kwd-group><kwd-group xml:lang="en"><kwd>breast cancer</kwd><kwd>intraoperative radiation therapy</kwd><kwd>radiation therapy</kwd><kwd>partial irradiation</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Forman D, Bray F, Brewster DH, et al. 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