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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">inovmed</journal-id><journal-title-group><journal-title xml:lang="ru">Инновационная медицина Кубани</journal-title><trans-title-group xml:lang="en"><trans-title>Innovative Medicine of Kuban</trans-title></trans-title-group></journal-title-group><issn pub-type="epub">2541-9897</issn><publisher><publisher-name>Scientific Research Institute – Ochapovsky Regional Clinical Hospital No. 1</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.35401/2541-9897-2023-26-1-21-28</article-id><article-id custom-type="elpub" pub-id-type="custom">inovmed-628</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Значение КТ-ангиографии в выявлении патологии экстракраниальных сонных и вертебральных артерий  у пациентов в острейшем периоде разрыва аневризм головного мозга</article-title><trans-title-group xml:lang="en"><trans-title>Role of CT Angiography in Detection of Extracranial Carotid  and Vertebral Artery Disease in Patients With Acutely Ruptured Intracranial Aneurysms</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6845-5613</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зяблова</surname><given-names>Е. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Zyablova</surname><given-names>E. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Зяблова Елена Игоревна, к. м. н., доцент, заведующая рентгеновским отделением; заведующая кафедрой лучевой диагностики № 2 ФПК и ППС</p><p>350086, Краснодар, ул. 1 Мая, 167</p></bio><bio xml:lang="en"><p>Elena I. Zyablova, Cand. Sci. (Med.), Associate Professor, Head of the Radiology Department; Head of Diagnostic Radiology Department No. 2, Faculty of Continuing Professional Development and Retraining</p><p>ulitsa 1 Maya 167, Krasnodar, 350086</p></bio><email xlink:type="simple">elenazyablova@inbox.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0572-1395</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Порханов</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Porhanov</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Порханов Владимир Алексеевич, академик РАН, профессор, д. м. н., главный врач; заведующий кафедрой онкологии с курсом торакальной хирургии</p><p>Краснодар</p></bio><bio xml:lang="en"><p>Vladimir A. Porhanov, Academician of the Russian Academy of Sciences, Professor, Dr. Sci. (Med.), Chief Physician; Head of the Oncology Department with the Thoracic Surgery Course</p><p>Krasnodar</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5649-2193</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Синицын</surname><given-names>В. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Sinitsyn</surname><given-names>V. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Синицын Валентин Евгеньевич, д. м. н., профессор, заведующий отделом лучевой диагностики; заведующий кафедрой лучевой диагностики и терапии факультета фундаментальной медицины</p><p>Москва</p></bio><bio xml:lang="en"><p>Valentin E. Sinitsyn, Dr. Sci. (Med.), Professor, Head of the Diagnostic Radiology Unit; Head of the Diagnostic Radiology and Radiation Therapy Department, Faculty of Fundamental Medicine</p><p>Moscow</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0483-032X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зяблова</surname><given-names>Д. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Zyablova</surname><given-names>D. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Зяблова Дарья Дмитриевна, студентка 6го курса лечебного факультета</p><p>Краснодар</p></bio><bio xml:lang="en"><p>Darya D. Zyablova, 6th-year student, Faculty of General Medicine</p><p>Krasnodar</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3644-6832</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Иванина</surname><given-names>Е. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Ivanina</surname><given-names>E. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Иванина Елена Евгеньевна, студентка 6го курса лечебного факультета</p><p>Краснодар</p></bio><bio xml:lang="en"><p>Elena E. Ivanina, 6th-year student, Faculty of General Medicine</p><p>Krasnodar</p></bio><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Научно-исследовательский институт – Краевая клиническая больница № 1 им. проф. С.В. Очаповского; Кубанский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Scientific Research Institute – Ochapovsky Regional Clinical Hospital No. 1; Kuban State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Медицинский научно-образовательный центр МГУ им. М.В. Ломоносова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Medical Scientific and Educational Center of Lomonosov Moscow State University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Кубанский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Kuban State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>30</day><month>03</month><year>2023</year></pub-date><volume>0</volume><issue>1</issue><fpage>21</fpage><lpage>28</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Зяблова Е.И., Порханов В.А., Синицын В.Е., Зяблова Д.Д., Иванина Е.Е., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Зяблова Е.И., Порханов В.А., Синицын В.Е., Зяблова Д.Д., Иванина Е.Е.</copyright-holder><copyright-holder xml:lang="en">Zyablova E.I., Porhanov V.A., Sinitsyn V.E., Zyablova D.D., Ivanina E.E.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.innovmedkub.ru/jour/article/view/628">https://www.innovmedkub.ru/jour/article/view/628</self-uri><abstract><sec><title>Введение</title><p>Введение: Компьютерная томография (КТ) головного мозга и КТ-ангиография (КТАГ) являются общепринятыми методами лучевой диагностики при обследовании пациентов с подозрением на острое внутримозговое кровоизлияние (ВМК) вследствие разрыва аневризм головного мозга (АГМ). Существуют различные протоколы выполнения КТ и КТАГ, в частности, зона исследования может ограничиваться только областью головного мозга или захватывать и брахиоцефальные артерии (БЦА) с дугой аорты с целью диагностики сопутствующей сосудистой патологии.</p></sec><sec><title>Цель исследования</title><p>Цель исследования: Определение вклада КТАГ в выявлении патологии экстракраниальных отделов БЦА и ее клинической значимости у пациентов, обследуемых по поводу острых внутримозговых кровоизлияний вследствие разрыва АГМ.</p></sec><sec><title>Материал и методы</title><p>Материал и методы: В исследование были включены 275 пациентов, пролеченных в нейрохирургическом отделении ГБУЗ «НИИ – ККБ № 1 им. проф. С.В. Очаповского» Министерства здравоохранения Краснодарского края по поводу острого нетравматического внутричерепного кровоизлияния (нВЧК) вследствие разрыва АГМ, с сентября 2017 по август 2020 г. Всем больным выполнялись КТ и КТАГ. При КТАГ область сканирования захватывала как интракраниальные, так и экстракраниальные артерии (от уровня дуги аорты до кожного покрова темени). Осуществлялся анализ наличия и форм патологических изменений БЦА (стенозы, окклюзии, патологические изгибы, гипоплазии).</p></sec><sec><title>Результаты</title><p>Результаты: Атеросклеротические поражения внутренних сонных артерий и позвоночных артерий были диагностированы у 95 пациентов (34,5% от общего количества больных, включенных в исследование). У 13 (4,7%) стенозы были гемодинамически значимыми. Выявлена высокая частота патологических изгибов БЦА (122 пациента, 44,3%) и гипоплазии позвоночных артерий (59 случаев, 21,5%). Установлено, что наличие стенозов БЦА и врожденных аномалий позвоночных (но не сонных) артерий было связано с более высокой частотой неблагоприятных исходов после эндоваскулярного лечения АГМ.</p></sec><sec><title>Заключение</title><p>Заключение: Протокол КТАГ при остром нВЧК должен включать изучение артерий как головы, так и шеи (до дуги аорты). Такой алгоритм позволяет выявить значительное число сопутствующих аномалий БЦА, которые имеют большое значение при планировании и успешном выполнении эндоваскулярного лечения интракраниальных АГМ.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction: Computed tomography (CT) and CT angiography are standard imaging modalities for suspected acute intracerebral hemorrhage due to ruptured intracranial aneurysms. In this clinical setting, several protocols of computed tomography and CT angiography may be implemented. The standard CT angiography protocol is limited to intracranial vessels. The extended protocol may also include carotid and vertebral arteries and the aortic arch.</p></sec><sec><title>Objective</title><p>Objective: To define the CT angiography role in detection of extracranial carotid and vertebral artery disease and clinical significance of this method for patients with suspected acute intracerebral hemorrhages due to ruptured intracranial aneurysms.</p></sec><sec><title>Materials and methods</title><p>Materials and methods: The study included 275 neurosurgical patients with acute nontraumatic intracranial hemorrhages due to ruptured intracranial aneurysms who were treated in Scientific Research Institute – Ochapovsky Regional Clinical Hospital No. 1 (Krasnodar, Russian Federation) from September 2017 to August 2020. Computed tomography and CT angiography were performed in all patients. The scanned area included both intracranial and extracranial arteries (an arch-to-vertex angiogram) to detect extracranial carotid and vertebral artery diseases such as stenoses, occlusions, tortuosity, and hypoplasia.</p></sec><sec><title>Results</title><p>Results: Atherosclerosis of internal carotid and vertebral arteries was diagnosed in 95 patients (34.5% of the total number of patients included in the study). In 13 (4.7%) patients these stenoses were hemodynamically significant. We identified a high frequency of tortuous carotid and vertebral arteries (122 cases, 44.3%) and vertebral artery hypoplasia (59 cases, 21.5%). The carotid and vertebral artery stenoses and congenital anomalies of vertebral arteries (however, not of carotid arteries) were associated with a higher incidence of unfavorable outcomes after endovascular treatment of intracranial aneurysms.</p></sec><sec><title>Conclusions</title><p>Conclusions: The optimal CT angiography protocol for acute nontraumatic intracranial hemorrhage should focus on the arteries of the head and neck (up to the aortic arch). This protocol shows higher detection rate of concomitant anomalies of carotid and vertebral arteries. These findings are important for planning and successful performance of endovascular treatment for intracranial aneurysms. </p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>КТ-ангиография</kwd><kwd>аневризма</kwd><kwd>субарахноидальное кровоизлияние</kwd><kwd>атеросклероз брахиоцефальных артерий</kwd><kwd>аномалии развития брахиоцефальных артерий</kwd></kwd-group><kwd-group xml:lang="en"><kwd>CT angiography</kwd><kwd>aneurysm</kwd><kwd>subarachnoid hemorrhage</kwd><kwd>atherosclerosis of the brachiocephalic arteries</kwd><kwd>brachiocephalic artery anomaly</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Всероссийское общество неврологов, Национальная ассоциация по борьбе с инсультом, Ассоциация нейрохирургов России и др. Клинические рекомендации «Ишемический инсульт и транзиторная ишемическая атака у взрослых». Министерство здравоохранения Российской Федерации. 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