inovmedИнновационная медицина КубаниInnovative Medicine of Kuban2541-9897Scientific Research Institute – Ochapovsky Regional Clinical Hospital No. 110.35401/2541-9897-2023-26-1-111-115inovmed-641Research ArticleОБЗОРЫREVIEWSСтресс-индуцированная кардиомиопатия (синдром такоцубо)Stress Cardiomyopathy (Takotsubo Cardiomyopathy)https://orcid.org/0000-0002-0783-8709ЯшинС. С.YashinS. S.

Яшин Сергей Сергеевич, старший преподаватель кафедры общей и клинической патологии

443099, Самара, ул. чапаевская, 89

Sergey S. Yashin, Senior Lecturer, Department of General and Clinical Pathology

ulitsa Chapaevskaya 89, Samara, 443099

s.s.yashin@samsmu.ruhttps://orcid.org/0000-0003-3168-3695КирееваА. О.KireevaA. O.

Киреева Анастасия Олеговна, студентка 4-го курса, Институт клинической медицины

Самара

Anastasia O. Kireeva, 4th-year student, Institute of Clinical Medicine

Samara

https://orcid.org/0000-0003-0838-5278СухачевП. А.SukhachevP. A.

Сухачев Павел Анатольевич, к. м. н., доцент кафедры общей и клинической патологии

Самара

Pavel A. Sukhachev, Cand. Sci. (Med.), Associate Professor, Department of General and Clinical Pathology

Samara

Самарский государственный медицинский университетРоссияSamara State Medical UniversityRussian Federation20233003202301111115Copyright © Яшин С.С., Киреева А.О., Сухачев П.А., 20232023Яшин С.С., Киреева А.О., Сухачев П.А.Yashin S.S., Kireeva A.O., Sukhachev P.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.innovmedkub.ru/jour/article/view/641

В статье рассматривается редкий клинический синдром стресс-индуцированной кардиомиопатии, также известный как синдром такоцубо. Несмотря на наличие противоречивых и неполных данных, определены основные звенья патогенеза данного синдрома, включая прямое токсическое воздействие катехоламинов на миокард, катехоламиновое оглушение миокарда, нарушения микроциркуляции.

На основании литературных данных систематизированы основные патоморфологические признаки синдрома такоцубо.

Определены основные направления клинической диагностики синдрома такоцубо.

In this article we describe a rare clinical condition of stress cardiomyopathy (takotsubo cardiomyopathy) for which we, despite controversy and lack of data, identified the main pathogenic pathways (including the direct toxic effect of catecholamines on the myocardium, catecholamine-mediated myocardial stunning, and microcirculation disorders). After the systematic review, we identified the distinct pathology features of this condition and new diagnostic strategies.

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The authors declare that there are no conflicts of interest present.