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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">inovmed</journal-id><journal-title-group><journal-title xml:lang="ru">Инновационная медицина Кубани</journal-title><trans-title-group xml:lang="en"><trans-title>Innovative Medicine of Kuban</trans-title></trans-title-group></journal-title-group><issn pub-type="epub">2541-9897</issn><publisher><publisher-name>Scientific Research Institute – Ochapovsky Regional Clinical Hospital No. 1</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.35401/2541-9897-2023-26-2-47-54</article-id><article-id custom-type="elpub" pub-id-type="custom">inovmed-672</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Роль компьютерной томографии в диагностике вирусной пневмонии, вызванной SARS-CoV-2 у детей</article-title><trans-title-group xml:lang="en"><trans-title>Role of chest computed tomography in the diagnosis of SARS-CoV-2 pneumonia in children</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6926-3165</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Корочкина</surname><given-names>Е. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Korochkina</surname><given-names>E. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Хасанова Ксения Андреевна, к. м. н., врач-рентгенолог, врач-радиолог, заведующая отделением лучевой диагностики</p><p>119049, Москва, 4-й Добрынинский переулок, дом 1/9</p></bio><bio xml:lang="en"><p>Ksenia A. Khasanova, Cand. Sci. (Med.), Radiologist, Head of the Diagnostic Radiology Unit</p><p>4 Dobryninskii pereulok, house 1/9, Moscow, 119049, Russian Federation</p></bio><email xlink:type="simple">evgeniakorochkina87@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3537-6262</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хасанова</surname><given-names>К. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Khasanova</surname><given-names>K. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Корочкина Евгения Сергеевна, врач-рентгенолог отделения лучевой диагностики</p><p>Москва</p></bio><bio xml:lang="en"><p>Evgeniya S. Korochkina, Radiologist, Diagnostic Radiology Unit</p><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Морозовская детская городская клиническая больница Департамента здравоохранения города Москвы</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Morozov Children’s City Clinical Hospital of the Moscow Healthcare Department</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>30</day><month>06</month><year>2023</year></pub-date><volume>0</volume><issue>2</issue><fpage>47</fpage><lpage>54</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Корочкина Е.С., Хасанова К.А., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Корочкина Е.С., Хасанова К.А.</copyright-holder><copyright-holder xml:lang="en">Korochkina E.S., Khasanova K.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.innovmedkub.ru/jour/article/view/672">https://www.innovmedkub.ru/jour/article/view/672</self-uri><abstract><sec><title>Введение</title><p>Введение: Первые ПЦР-подтвержденные случаи COVID-19 у детей в России были зарегистрированы в начале марта 2020 г. Компьютерная томография органов грудной клетки (КТ ОГК) представляет собой наиболее чувствительный метод лучевой диагностики, позволяющий диагностировать ранние признаки вирусного поражения легких. В настоящее время имеются ограниченные данные об особенностях клинических и лабораторных проявлений COVID-19 у детей и их корреляции с данными инструментальных методов диагностики, что дает основание считать изучение особенностей COVID-19 у детей важным вопросом современной медицины и определяет актуальность представленной работы.</p></sec><sec><title>Цель исследования</title><p>Цель исследования: Определить диагностическую эффективность и корреляционную связь между лабораторными, клиническими и КТ-данными у детей и подростков с коронавирусной инфекцией COVID-19.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы: С февраля 2020 по февраль 2021 г. в ГБУЗ «Морозовская ДГКБ ДЗМ» были госпитализированы 372 пациента с подозрением на новую коронавирусную инфекцию. В данное ретроспективное исследование вошли 158 больных с положительным РНК SARS-CoV-2 в мазках из рото- и носоглотки, результатами IgM и IgG, изменениями в общем анализе, биохимии крови и коагулограмме, клинической симптоматикой и подозрением на наличие пневмонии, вызванной вирусом SARS-CoV-2 по результатам КТ ОГК.</p></sec><sec><title>Результаты</title><p>Результаты: При диагностике пневмонии, вызванной SARS-CoV-2, по данным КТ ОГК показатели чувствительности и специфичности составили 98 и 85% соответственно. В нашем исследовании фактором, негативно влияющим на диагностическую эффективность метода, являлось наличие артефактов от дыхания у маленьких детей на фоне общей анестезии. В данной группе чувствительность и специфичность метода составили 89 и 71% соответственно.</p></sec><sec><title>Заключение</title><p>Заключение: Наличие признаков вирусной пневмонии на КТ ОГК статистически значимо чаще встречалось у детей с кашлем, признаками дыхательной недостаточности, наличием лимфопении, повышением Д-димера и С-реактивного белка. Таким образом, выявление одного из этих признаков или их сочетание может быть основанием для проведения КТ ОГК у ребенка с подозрением на течение вирусной пневмонии, вызванной SARS-CoV-2.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Background</title><p>Background: First PCR-confirmed COVID-19 cases among Russian children were reported in early March 2020. Chest computed tomography (CT) is the most sensitive imaging modality in diagnosing early signs of viral lung damage. Limited data are available on clinical and laboratory features of COVID-19 in children and on their correlation with imaging findings. Studying COVID-19 features in children is crucial for modern medicine, which makes our research relevant.</p></sec><sec><title>Objective</title><p>Objective: To determine the diagnostic efficacy and correlation between laboratory, clinical, and CT findings in children and adolescents with COVID-19.</p></sec><sec><title>Materials and methods</title><p>Materials and methods: From February 2020 to February 2021 372 patients with suspected COVID-19 were admitted to Morozov Children’s City Clinical Hospital (Moscow, Russian Federation). This retrospective study included 158 patients who presented with positive oropharyngeal and nasopharyngeal swab results, IgM and IgG test results, changes in complete blood count, blood biochemistry and coagulation test results, clinical symptoms, and suspected SARS-CoV-2 pneumonia based on chest CT findings.</p></sec><sec><title>Results</title><p>Results: Chest CT sensitivity and specificity for diagnosis of SARS-CoV-2 pneumonia were up to 98% and 85%, respectively. We considered that severe respiratory motion artifacts in young children under general anesthesia adversely affected the diagnostic efficacy. Sensitivity and specificity in this group were up to 89% and 71%, respectively.</p></sec><sec><title>Conclusions</title><p>Conclusions: Viral pneumonia signs on chest CT scans were statistically significantly more frequent in children with cough, respiratory failure signs, lymphopenia, and increased D-dimer and C-reactive protein levels. One of these signs or a combination of them are an indication for chest CT in children with suspected SARS-CoV-2 pneumonia.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>COVID-19</kwd><kwd>пневмония</kwd><kwd>вызванная SARS-CoV-2</kwd><kwd>компьютерная томография</kwd></kwd-group><kwd-group xml:lang="en"><kwd>COVID-19</kwd><kwd>SARS-CoV-2 pneumonia</kwd><kwd>chest computed tomography</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Коронавирусная инфекция – COVID-19, 10-я редакция с изменениями от 15.07.2020. MedElement. Дата обращения: 06.08.2022. https://diseases.medelement.com/disease/коронавирусная%20-инфекция-2019-ncov-кп-мз-рк/16390</mixed-citation><mixed-citation xml:lang="en">Coronavirus infection – COVID19, 10th amended version dated July 15, 2020. MedElement. Accessed August 6, 2022. 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