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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">inovmed</journal-id><journal-title-group><journal-title xml:lang="ru">Инновационная медицина Кубани</journal-title><trans-title-group xml:lang="en"><trans-title>Innovative Medicine of Kuban</trans-title></trans-title-group></journal-title-group><issn pub-type="epub">2541-9897</issn><publisher><publisher-name>Scientific Research Institute – Ochapovsky Regional Clinical Hospital No. 1</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.35401/2541-9897-2023-26-2-55-62</article-id><article-id custom-type="elpub" pub-id-type="custom">inovmed-673</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Опыт применения автоматизированной программы Olea Sphere для количественной оценки ишемического повреждения паренхимы головного мозга у пациентов с острым нарушением мозгового кровообращения</article-title><trans-title-group xml:lang="en"><trans-title>Quantitative assessment of the ischemic damage to the brain parenchyma in patients with acute cerebrovascular accident using the Olea Sphere automated software</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0315-5502</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ясакова</surname><given-names>Е. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Yasakova</surname><given-names>E. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ясакова Елена Петровна, к. м. н., врач-рентгенолог, рентгеновское отделение; доцент кафедры лучевой диагностики № 2 ФПК и ППС</p><p>350086, Краснодарский край, Краснодар, ул. 1 Мая, д. 167</p></bio><bio xml:lang="en"><p>Elena P. Yasakova, Cand. Sci. (Med.), Radiologist, Radiology Department; Associate Professor of Diagnostic Radiology Department No. 2, Faculty of Continuing Professional Development and Retraining</p><p>ulitsa 1 Maya 167, Krasnodar, 350086, Russian Federation</p></bio><email xlink:type="simple">eliz2007@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0000-6725-2745</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шевченко</surname><given-names>Е. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Shevchenko</surname><given-names>E. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шевченко Евгения Геннадиевна, врач-рентгенолог, рентгеновское отделение; ассистент кафедры лучевой диагностики № 2 ФПК и ППС</p><p>Краснодар</p></bio><bio xml:lang="en"><p>Evgeniya G. Shevchenko, Radiologist, Radiology Department; Assistant, Diagnostic Radiology Department No. 2, Faculty of Continuing Professional Development and Retraining</p><p>Krasnodar</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4392-7848</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ефимов</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Efimov</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ефимов Виталий Владимирович, врач-рентгенхирург, отделение рентгенохирургических методов диагностики и лечения</p><p>Краснодар</p></bio><bio xml:lang="en"><p>Vitaliy V. Efimov, X-ray Surgeon, Department of X-ray Surgical Methods of Diagnosis and Treatment</p><p>Krasnodar</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6845-5613</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зяблова</surname><given-names>Е. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Zyablova</surname><given-names>E. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Зяблова Елена Игоревна, к. м. н., доцент, заведующая рентгеновским отделением; заведующая кафедрой лучевой диагностики № 2 ФПК и ППС,</p><p>Краснодар</p></bio><bio xml:lang="en"><p>Elena I. Zyablova, Cand. Sci. (Med.), Associate Professor, Head of the Radiology Department; Head of Diagnostic Radiology Department No. 2, Faculty of Continuing Professional Development and Retraining</p><p>Krasnodar</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Научно-исследовательский институт – Краевая клиническая больница № 1 им. проф. С.В. Очаповского; Кубанский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Scientific Research Institute — Ochapovsky Regional Clinical Hospital No. 1; Kuban State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Научно-исследовательский институт – Краевая клиническая больница № 1 им. проф. С.В. Очаповского</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Scientific Research Institute — Ochapovsky Regional Clinical Hospital No. 1</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>30</day><month>06</month><year>2023</year></pub-date><volume>0</volume><issue>2</issue><fpage>55</fpage><lpage>62</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ясакова Е.П., Шевченко Е.Г., Ефимов В.В., Зяблова Е.И., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Ясакова Е.П., Шевченко Е.Г., Ефимов В.В., Зяблова Е.И.</copyright-holder><copyright-holder xml:lang="en">Yasakova E.P., Shevchenko E.G., Efimov V.V., Zyablova E.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.innovmedkub.ru/jour/article/view/673">https://www.innovmedkub.ru/jour/article/view/673</self-uri><abstract><sec><title>Цель</title><p>Цель: Оценить возможности автоматизированной программы Olea Sphere при количественной оценке ишемического повреждения паренхимы головного мозга при выполнении компьютерной томографии у пациентов с острым нарушением мозгового кровообращения (ОНМК), ее роль в выборе оптимальной тактики лечения в повседневной клинической практике.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы: Ретроспективно проанализированы данные 129 пациентов, обследованных с подозрением на ОНМК, которым при поступлении в стационар в течение 24 ч была выполнена перфузионная компьютерная томография. По данным Olea Sphere оценивали объем ядра инфаркта как области с относительным мозговым кровотоком (rCBF) менее 40%, объем пенумбры (Tmax &gt; 6 сек.) и их соотношение.</p></sec><sec><title>Результаты</title><p>Результаты: Автоматизированная станция Olea Sphere позволила количественно оценить ишемические изменения паренхимы головного мозга. При этом средний объем ядра инфаркта у 129 пациентов, по данным станции, составил 21,95 (1–206) мл, средний объем пенумбры – 57,01 (2–357) мл, соотношение ядро/пенумбра – 2,65, среднее время от момента выполнения КТ до начала лечения – 1,2 (0,9–1,9) ч. Благодаря количественной обработке данных на станции Olea Sphere у пациентов с ишемическим инсультом были определены показания к рентгенваскулярным методам лечения: процедура тромбэкстракции в остром периоде выполнена 51 больному (72,8%), транслюминальная балонная ангиопластика с установкой стента – 12 (17,1%), каротидная эндартерэктомия – 5 (9,6%) больным в отдаленном периоде.</p></sec><sec><title>Выводы</title><p>Выводы: Выявлены возможности автоматизированной программы Olea Sphere в оценке ишемических изменений головного мозга, плюсы ее использования для принятия решений у пациентов с ОНМК в неотложных условиях.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Objective</title><p>Objective: To evaluate the capabilities of the Olea Sphere automated software for the quantitative assessment of ischemic damage to the brain parenchyma during computed tomography (CT) in patients with acute cerebrovascular accident and its role in choosing the optimal treatment strategy in everyday clinical practice.</p></sec><sec><title>Materials and methods</title><p>Materials and methods: We retrospectively analyzed the data from 129 patients with suspected stroke who underwent perfusion CT within 24 hours of admission to the hospital. The Olea Sphere data were used to assess the volume of the infarct core, which was defined as an area with a relative cerebral blood flow less than 40%, the volume of the penumbra area, where Tmax exceeded 6 s, and ultimately the core-penumbra ratio.</p></sec><sec><title>Results</title><p>Results: With the Olea Sphere automated software, we were able to assess the volume of the ischemic changes in the brain parenchyma, particularly, the average volume of the infarct core in 129 patients was 21.95 (1-206) ml, the average volume of the penumbra area was 57.01 (2-357) ml, the core-penumbra ratio was 2.65, and mean time from CT to the start of treatment was 1.2 (0.9-1.9) hours. This quantitative data processing powered by the Olea Sphere provided the indications for the following endovascular treatment in patients with stroke: thrombus extraction in the acute period was performed in 51 patients (72.8%), transluminal balloon angioplasty with stent placement – in 12 patients (17.1%), and carotid endarterectomy in the long-term period – in 5 (9.6%) patients.</p></sec><sec><title>Conclusions</title><p>Conclusions: We discovered that the Olea Sphere automated software can be used to assess ischemic changes in the brain and to make decisions related to patients with acute cerebrovascular accident in emergency conditions.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>перфузионная компьютерная томография</kwd><kwd>острое нарушение мозгового кровообращения</kwd><kwd>ишемический инсульт</kwd><kwd>Olea Sphere</kwd></kwd-group><kwd-group xml:lang="en"><kwd>perfusion computed tomography</kwd><kwd>acute cerebrovascular accident</kwd><kwd>ischemic stroke</kwd><kwd>Olea Sphere</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Клочихина О.А., Шпрах В.В., Стаховская Л.В., Полунина О.С., Полунина Е.А. 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