<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">inovmed</journal-id><journal-title-group><journal-title xml:lang="ru">Инновационная медицина Кубани</journal-title><trans-title-group xml:lang="en"><trans-title>Innovative Medicine of Kuban</trans-title></trans-title-group></journal-title-group><issn pub-type="epub">2541-9897</issn><publisher><publisher-name>Scientific Research Institute – Ochapovsky Regional Clinical Hospital No. 1</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.35401/2541-9897-2023-8-4-15-24</article-id><article-id custom-type="elpub" pub-id-type="custom">inovmed-761</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Исходы лечения пациентов с острым коронарным синдромом с подъемом сегмента ST и развившимся феноменом no/slow-reflow, в зависимости от возраста</article-title><trans-title-group xml:lang="en"><trans-title>Treatment Outcomes in STEMI Patients  With No/Slow-Reflow Phenomenon, Depending on Age</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0277-1880</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сазанов</surname><given-names>Г. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sazanov</surname><given-names>G. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сазанов Григорий Вячеславович, врач по рентген-эндоваскулярной диагностике и лечению, отделение рентгенохирургических методов диагностики и лечения</p><p>355000, Ставрополь, ул. Семашко 1</p></bio><bio xml:lang="en"><p>Grigoriy V. Sazanov, Interventional Radiologist, Division of Image­Guided Diagnosis and Surgery</p><p>ulitsa Semashko 1, Stavropol, 355000</p></bio><email xlink:type="simple">mc_sagr@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5335-5062</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шугушев</surname><given-names>З. Х.</given-names></name><name name-style="western" xml:lang="en"><surname>Shugushev</surname><given-names>Z. Kh.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шугушев Заурбек Хасанович, д. м. н., профессор, заведующий кафедрой сердечно-­сосудистой хирургии, факультет непрерывного медицинского образования</p><p>Москва</p></bio><bio xml:lang="en"><p>Zaurbek Kh. Shugushev, Dr. Sci. (Med.), Professor, Head of the Cardiovascular Surgery Department, Faculty of Continuous Medical Education</p><p>Moscow</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5794-1085</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Белоконь</surname><given-names>О. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Belokon</surname><given-names>O. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Белоконь Олег Сергеевич, к. м. н., заведующий отделением рентгенохирургических методов диагностики и лечения</p><p>Ставрополь</p></bio><bio xml:lang="en"><p>Oleg S. Belokon, Cand. Sci. (Med.), Head of the Division of Image­Guided Diagnosis and Surgery</p><p>Stavropol</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5679-1775</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ермаков</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Ermakov</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ермаков Сергей Васильевич, к. м. н., врач-­невролог, нейрохирургическое отделение № 1, врач по рентген-эндоваскулярной диагностике и лечению отделения рентгенохирургических методов диагностики и лечения</p><p>Ставрополь</p></bio><bio xml:lang="en"><p>Sergey V. Ermakov, Cand. Sci. (Med.), Neurologist, Neurosurgery Unit No. 1, Interventional Radiologist, Division of ImageGuided Diagnosis and Surgery</p><p>Stavropol</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0008-2889-5500</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Муковникова</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Mukovnikova</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Муковникова Анна Васильевна, врач клинической лабораторной диагностики, клинико­-диагностическая лаборатория</p><p>Ставрополь</p></bio><bio xml:lang="en"><p>Anna V. Mukovnikova, Clinical Pathologist, Clinical Diagnostic Laboratory</p><p>Stavropol</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Ставропольская краевая клиническая больница</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Stavropol Regional Clinical Hospital</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Медицинский институт Российского университета дружбы народов</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Institute of Medicine,Patrice Lumumba Peoples’ Friendship University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>30</day><month>12</month><year>2023</year></pub-date><volume>0</volume><issue>4</issue><fpage>15</fpage><lpage>24</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Сазанов Г.В., Шугушев З.Х., Белоконь О.С., Ермаков С.В., Муковникова А.В., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Сазанов Г.В., Шугушев З.Х., Белоконь О.С., Ермаков С.В., Муковникова А.В.</copyright-holder><copyright-holder xml:lang="en">Sazanov G.V., Shugushev Z.K., Belokon O.S., Ermakov S.V., Mukovnikova A.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.innovmedkub.ru/jour/article/view/761">https://www.innovmedkub.ru/jour/article/view/761</self-uri><abstract><sec><title>Актуальность</title><p>Актуальность: Острый коронарный синдром (ОКС) характеризуется внезапным снижением кровоснабжения сердца и, по оценкам экспертов, каждый год ОКС диагностируется более чем у 7 млн человек в мире.</p></sec><sec><title>Цель исследования</title><p>Цель исследования: Оценка рисков возникновения феноменов no/slow­reflow и исходов лечения пациентов c ОКС с подъемом сегмента ST (ОКСпST) в различных возрастных группах.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы: Выполнен анализ результатов лечения 535 пациентов с ОКСпST. В зависимости от возраста пациенты были распределены на 4 группы:1-­я группа – 33 пациента моложе 44 лет, 2­-я группа – 209 пациентов в возрасте от 45 до 59 лет, 3-­я группа – 247 пациентов пожилого возраста (60–74 года), 4­-я группа – 46 пациентов старческого возраста (от 75 до 80 лет).</p></sec><sec><title>Результаты</title><p>Результаты: В ходе исследования установлено, что в молодом возрасте ОКСпST чаще встречается у мужчин, а в пожилом и старческом возрасте увеличивается количество женщин, достигая 37% (против 3% среди молодых пациентов). Также получены данные, что с увеличением возраста пациентов для коррекции поражения инфаркт­-связанной коронарной артерии требуется статистически значимо большее количество коронарных стентов (p = 0,009, критерий Краскела­-Уоллиса). Время, необходимое для выполнения чрескожного коронарного вмешательства у пациентов пожилого и старческого возраста было статистически значимо выше, чем у молодых пациентов (p = 0,022, критерий Краскела-­Уоллиса).</p></sec><sec><title>Заключение</title><p>Заключение: В ходе исследования установлено, что частота летальных исходов была выше у пациентов с ОКСпST старших возрастных групп (9,30 и 10,90%). У молодых пациентов летальных случаев в 30­-дневный период наблюдения не зарегистрировано. У пациентов среднего возраста летальность составила 3,3%. Представленные различия были статистически значимы (p = 0,016, Хи­-квадрат Пирсона). Проведенный анализ общей выживаемости у пациентов, в зависимости от возрастной группы, выявил статистически значимые различия (тест отношения правдоподобия, p = 0,006).</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Objective</title><p>Objective: To assess the risks of no/slow-­reflow phenomena and treatment outcomes in patients with ST­-segment elevation myocardial infarction (STEMI) from different age groups.</p></sec><sec><title>Materials and methods</title><p>Materials and methods: We analyzed treatment outcomes of 535 STEMI patients who were divided into 4 groups based on their age: 33 patients younger than 44 years (group 1), 209 patients aged 45 to 59 years (group 2), 247 patients aged 60 to 74 years (group 3), and 46 patients aged 75 to 80 years (group 4).</p></sec><sec><title>Results</title><p>Results: Our study revealed that among the young people STEMI is more often found in men, whereas in the older population the number of women increases accounting for 37% (compare with 3% among the young patients). It was also shown that with age, statistically significantly more coronary stents (P = .009, Kruskal­Wallis test) are needed to repair an infarct-­related coronary artery lesion. The time required to perform a percutaneous coronary intervention was statistically significantly higher in the older adults than in the young patients (P = .022, Kruskal­-Wallis test).</p></sec><sec><title>Conclusions</title><p>Conclusions: Our study found that the frequency of deaths was higher in STEMI patients from the older age groups (9.30% and 10.90%), whereas in the young patients, no deaths were registered during the 30­-day follow­up. In the middle­aged patients, mortality accounted for 3.3%. The reported differences were statistically significant (P = .016, Pearson’s χ2). The analysis of overall survival based on the age group revealed statistically significant differences (likelihood ratio test, P = .006).</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>острый коронарный синдром с подъемом сегмента ST</kwd><kwd>чрескожные коронарные вмешательства</kwd><kwd>феномен no-reflow/slow-reflow</kwd></kwd-group><kwd-group xml:lang="en"><kwd>STEMI</kwd><kwd>percutaneous coronary interventions</kwd><kwd>no-reflow/slow-reflow phenomenon</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Bhatt DL, LopesRD, HarringtonRA. Diagnosis and treatment of acute coronary syndromes: a review. JAMA. 2022;327(7):662–675. Published correction appears in JAMA. 2022;327(17):1710. PMID: 35166796. https://doi.org/10.1001/jama.2022.0358</mixed-citation><mixed-citation xml:lang="en">Bhatt DL, LopesRD, HarringtonRA. Diagnosis and treatment of acute coronary syndromes: a review. JAMA. 2022;327(7):662–675. Published correction appears in JAMA. 2022;327(17):1710. PMID: 35166796. https://doi.org/10.1001/jama.2022.0358</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Rezkalla SH, Kloner RA. Coronary no-reflow phenomenon. Curr Treat Options Cardiovasc Med. 2005;7(1):75–80. PMID: 15913506. https://doi.org/10.1007/s11936-005-0008-0</mixed-citation><mixed-citation xml:lang="en">Rezkalla SH, Kloner RA. Coronary no-reflow phenomenon. Curr Treat Options Cardiovasc Med. 2005;7(1):75–80. PMID: 15913506. https://doi.org/10.1007/s11936-005-0008-0</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Claessen BE, Maehara A, Fahy M, Xu K, Stone GW, Mintz GS. Plaque composition by intravascular ultrasound and distal embolization after percutaneous coronary intervention. JACC Cardiovasc Imaging. 2012;5(3 Suppl):S111–S118. PMID: 22421225. https://doi.org/10.1016/j.jcmg.2011.11.018</mixed-citation><mixed-citation xml:lang="en">Claessen BE, Maehara A, Fahy M, Xu K, Stone GW, Mintz GS. Plaque composition by intravascular ultrasound and distal embolization after percutaneous coronary intervention. JACC Cardiovasc Imaging. 2012;5(3 Suppl):S111–S118. PMID: 22421225. https://doi.org/10.1016/j.jcmg.2011.11.018</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">De Luca G, van ‘t Hof AW, de Boer MJ, et al. Impaired myocardial perfusion is a major explanation of the poor outcome observed in patients undergoing primary angioplasty for ST-segment-elevation myocardial infarction and signs of heart failure. Circulation. 2004;109(8):958–961. PMID: 14981008. https://doi.org/10.1161/01.CIR.0000120504.31457.28</mixed-citation><mixed-citation xml:lang="en">De Luca G, van ‘t Hof AW, de Boer MJ, et al. Impaired myocardial perfusion is a major explanation of the poor outcome observed in patients undergoing primary angioplasty for ST-segment-elevation myocardial infarction and signs of heart failure. Circulation. 2004;109(8):958–961. PMID: 14981008. https://doi.org/10.1161/01.CIR.0000120504.31457.28</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Rezkalla SH, Stankowski RV, Hanna J, Kloner RA. Management of no-reflow phenomenon in the catheterization laboratory. JACC Cardiovasc Interv. 2017;10(3):215–223. Published correction appears in JACC Cardiovasc Interv. 2017;10(12):1282. PMID: 28183461. https://doi.org/10.1016/j.jcin.2016.11.059</mixed-citation><mixed-citation xml:lang="en">Rezkalla SH, Stankowski RV, Hanna J, Kloner RA. Management of no-reflow phenomenon in the catheterization laboratory. JACC Cardiovasc Interv. 2017;10(3):215–223. Published correction appears in JACC Cardiovasc Interv. 2017;10(12):1282. PMID: 28183461. https://doi.org/10.1016/j.jcin.2016.11.059</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Wang J, Toan J, Zhou S. New insights into the role of mitochondria in cardiac microvascular ischemia/reperfusion injury. Angiogenesis. 2020;23(3):299–314. PMID: 32246225. https://doi.org/10.1007/s10456-020-09720-2</mixed-citation><mixed-citation xml:lang="en">Wang J, Toan J, Zhou S. New insights into the role of mitochondria in cardiac microvascular ischemia/reperfusion injury. Angiogenesis. 2020;23(3):299–314. PMID: 32246225. https://doi.org/10.1007/s10456-020-09720-2</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Prasad A, Stone GW, Stuckey TD, et al. Impact of diabetes mellitus on myocardial perfusion after primary angioplasty in patients with acute myocardial infarction. J Am Coll Cardiol. 2005;45(4):508–514. PMID: 15708696. https://doi.org/10.1016/j.jacc.2004.10.054</mixed-citation><mixed-citation xml:lang="en">Prasad A, Stone GW, Stuckey TD, et al. Impact of diabetes mellitus on myocardial perfusion after primary angioplasty in patients with acute myocardial infarction. J Am Coll Cardiol. 2005;45(4):508–514. PMID: 15708696. https://doi.org/10.1016/j.jacc.2004.10.054</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">TimmerJR, van der Horst IC, de Luca G, et al; Zwolle Myocardial Infarction Study Group. Comparison of myocardial perfusion after successful primary percutaneous coronary intervention in patients with ST-elevation myocardial infarction with versus without diabetes mellitus. Am J Cardiol. 2005;95(11):1375–1377. PMID: 15904649. https://doi.org/10.1016/j.amjcard.2005.01.088</mixed-citation><mixed-citation xml:lang="en">TimmerJR, van der Horst IC, de Luca G, et al; Zwolle Myocardial Infarction Study Group. Comparison of myocardial perfusion after successful primary percutaneous coronary intervention in patients with ST-elevation myocardial infarction with versus without diabetes mellitus. Am J Cardiol. 2005;95(11):1375–1377. PMID: 15904649. https://doi.org/10.1016/j.amjcard.2005.01.088</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Iwakura K, Ito H, Kawano S, et al. Predictive factors for development of the no-reflow phenomenon in patients with reperfused anterior wall acute myocardial infarction. J Am Coll Cardiol. 2001;38(2):472–477. PMID: 11499740. https://doi.org/10.1016/s0735-1097(01)01405-x</mixed-citation><mixed-citation xml:lang="en">Iwakura K, Ito H, Kawano S, et al. Predictive factors for development of the no-reflow phenomenon in patients with reperfused anterior wall acute myocardial infarction. J Am Coll Cardiol. 2001;38(2):472–477. PMID: 11499740. https://doi.org/10.1016/s0735-1097(01)01405-x</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Namazi M, Mahmoudi E, Safi M, et al. The no-reflow phenomenon: is it predictable by demographic factors and routine laboratory data?. Acta Biomed. 2021;92(5):e2021297. PMID: 34738591. PMCID: PMC8689329. https://doi.org/10.23750/abm.v92i5.10053</mixed-citation><mixed-citation xml:lang="en">Namazi M, Mahmoudi E, Safi M, et al. The no-reflow phenomenon: is it predictable by demographic factors and routine laboratory data?. Acta Biomed. 2021;92(5):e2021297. PMID: 34738591. PMCID: PMC8689329. https://doi.org/10.23750/abm.v92i5.10053</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Сазанов Г.В., Белоконь О.С. Влияние предилатации на частоту возникновения феномена no/slow-reflow у пациентов с острым коронарным синдромом с подъёмом сегмента ST. Казанский медицинский журнал. 2020;101(2):284–288. Исправление к статье опубликовано в: Казанский медицинский журнал. 2020;101(3):480. https://doi.org/10.17816/KMJ2020-284</mixed-citation><mixed-citation xml:lang="en">Sazanov GV, Belokon’ OS. The effect of predilation on the incidence of the no/slow-reflow phenomenon in patients with acute coronary syndrome with ST segment elevation. Kazan Medical Journal. 2020;101(2):284–288. Published correction appears in Kazan Medical Journal. 2020;101(3):480. (In Russ.). https://doi.org/10.17816/KMJ2020-284</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Shakiba M, Salari A, Mirbolouk F, Sotudeh N, Nikfarjam S. Clinical, laboratory, and procedural predictors of no-reflow in patients undergoing primary percutaneous coronary intervention. J Tehran Heart Cent. 2020;15(2):50–56. PMID: 33552194. PMCID: PMC7825467. https://doi.org/10.18502/jthc.v15i2.4183</mixed-citation><mixed-citation xml:lang="en">Shakiba M, Salari A, Mirbolouk F, Sotudeh N, Nikfarjam S. Clinical, laboratory, and procedural predictors of no-reflow in patients undergoing primary percutaneous coronary intervention. J Tehran Heart Cent. 2020;15(2):50–56. PMID: 33552194. PMCID: PMC7825467. https://doi.org/10.18502/jthc.v15i2.4183</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Kalayci A, Oduncu V, Karabay CY, et al. Outcomes of direct stenting in patients with ST-elevated myocardial. Herz. 2018;43(5):447–454. PMID: 28616647. https://doi.org/10.1007/s00059-017-4581-2</mixed-citation><mixed-citation xml:lang="en">Kalayci A, Oduncu V, Karabay CY, et al. Outcomes of direct stenting in patients with ST-elevated myocardial. Herz. 2018;43(5):447–454. PMID: 28616647. https://doi.org/10.1007/s00059-017-4581-2</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Berger PB, Ellis SG, Holmes DR, et al. Relationship between delay in performing direct coronary angioplasty and early clinical outcome in patients with acute myocardial infarction: results from the global use of strategies to open occluded arteries in Acute Coronary Syndromes (GUSTO-IIb) trial. Circulation. 1999;100(1):14–20. PMID: 10393675. https://doi.org/10.1161/01.cir.100.1.14</mixed-citation><mixed-citation xml:lang="en">Berger PB, Ellis SG, Holmes DR, et al. Relationship between delay in performing direct coronary angioplasty and early clinical outcome in patients with acute myocardial infarction: results from the global use of strategies to open occluded arteries in Acute Coronary Syndromes (GUSTO-IIb) trial. Circulation. 1999;100(1):14–20. PMID: 10393675. https://doi.org/10.1161/01.cir.100.1.14</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Mehta RH, Harjai KJ, Cox D, et al; Primary Angioplasty in Myocardial Infarction (PAMI) Investigators. Clinical and angiographic correlates and outcomes of suboptimal coronary flow inpatients with acute myocardial infarction undergoing primary percutaneous coronary intervention. J Am Coll Cardiol. 2003;42(10):1739–1746. PMID: 14642681. https://doi.org/10.1016/j.jacc.2003.07.012</mixed-citation><mixed-citation xml:lang="en">Mehta RH, Harjai KJ, Cox D, et al; Primary Angioplasty in Myocardial Infarction (PAMI) Investigators. Clinical and angiographic correlates and outcomes of suboptimal coronary flow inpatients with acute myocardial infarction undergoing primary percutaneous coronary intervention. J Am Coll Cardiol. 2003;42(10):1739–1746. PMID: 14642681. https://doi.org/10.1016/j.jacc.2003.07.012</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Сазанов Г.В., Шугушев З.Х., Белоконь О.С., Ермаков С.В., Хрипунова А.А. Бужирование инфаркт связанной коронарной артерии как метод снижения частоты встречаемости феномена no-reflow у пациентов с острым коронарным синдромом с подъемом сегмента ST. Инновационная медицина Кубани. 2023;8(3):54–61. https://doi.org/10.35401/25419897-2023-26-3-54-61</mixed-citation><mixed-citation xml:lang="en">Sazanov GV, Shugushev ZKh, Belokon OS, Ermakov SV, Khripunova AA. Dilation of the infarct-related coronary artery to reduce the incidence of the no-reflow phenomenon in STEMI patients. Innovative Medicine of Kuban. 2023;8(3):54–61. (In Russ.). https://doi.org/10.35401/2541-9897-2023-26-3-54-61</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
