inovmedИнновационная медицина КубаниInnovative Medicine of Kuban2541-9897Scientific Research Institute – Ochapovsky Regional Clinical Hospital No. 110.35401/2541-9897-2023-8-4-68-73inovmed-767Research ArticleОРИГИНАЛЬНЫЕ СТАТЬИORIGINAL ARTICLESОценка качества жизни пациентов после туберкулеза легкихAssessment of Health-Related Quality of Life in Post Pulmonary Tuberculosis Patientshttps://orcid.org/0000-0002-9917-3379КумарК.KumarK.

Кишор Кумар, соискатель ученой степени PhD, кафедра респираторной медицины

Ченнай

Kishore Kumar, PhD Research Scholar, Department of Respiratory Medicine

Chennai

https://orcid.org/0009-0006-4344-6805ПерумалК.PerumalK.

Коушалья Перумал, специалист по респираторной терапии и тьютор, кафедра пульмонологии

Аммапеттай

Koushalya Perumal, Respiratory Therapist and Tutor, Department of Pulmonary Medicine

Ammapettai

https://orcid.org/0000-0002-8743-149XНарасимханМ.NarasimhanM.

Минакши Нарасимхан, профессор и заведующая кафедрой, кафедра респираторной медицины

Городок здоровья Четтинада, Раджив Ганди Салаи, Келамбаккам – 603 103, Ченнай, шт. Тамилнад

Meenakshi Narasimhan, Professor and Department Head, Department of Respiratory Medicine

Chettinad Health City, Rajiv Gandhi Salai, Kelambakkam – 603 103, Chennai, Tamil Nadu

respiratorymedicine@care.edu.inБольница и исследовательский институт Четтинада, Четтинадская академия исследований и образованияИндияChettinad Hospital and Research Institute, Chettinad Academy of Research and EducationIndiaМедицинский колледж и научно-исследовательский институт Шри Сатья СаиИндияShri Sathya Sai Medical College and Research InstituteIndia202330122023046873Copyright © Кумар К., Перумал К., Нарасимхан М., 20232023Кумар К., Перумал К., Нарасимхан М.Kumar K., Perumal K., Narasimhan M.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.innovmedkub.ru/jour/article/view/767

Во всем мире туберкулез остается важной проблемой общественного здравоохранения и ведущей причиной смертности. Термин «посттуберкулезные изменения» включает различные проявления после успешного лечения туберкулеза, такие как респираторные симптомы, снижение функции дыхания, остаточные повреждения легких на рентгенограмме, непереносимость физической нагрузки и снижение качества жизни, связанного со здоровьем.

Целью нашей работы являлась оценка качества жизни у пациентов с посттуберкулезными изменениями посредством опросника SF­-36. Наше исследование включало пациентов с посттуберкулезными изменениями, которые завершили противотуберкулезное лечение и обратились в амбулаторное отделение с диагнозом «посттуберкулезные изменения» или «последствия туберкулеза легких». Всего в исследовании приняли участие 92 пациента в возрасте 18–81 год, предоставившие письменное информированное согласие. Воздействие биотоплива на дыхательные пути было статистически значимым для компонентов психического здоровья (р < 0,05). У пациентов с обструктивным заболеванием дыхательных путей, перенесших туберкулез легких, наблюдалось снижение качества жизни, связанного как с физическим, так и психическим здоровьем. Наши результаты демонстрируют высокую распространенность сопутствующих заболеваний. Значимой связи между компонентами физического и психического здоровья обнаружено не было. Таким образом, мы подчеркиваем необходимость психологического консультирования, легочной реабилитации и последующего наблюдения в рамках целостного подхода к лечению даже после микробиологического излечения от последствий туберкулеза легких и рекомендуем ранний скрининг качества жизни, связанного со здоровьем, для улучшения уровня жизни пациентов.

Globally, tuberculosis remains an important public health problem and a major leading cause of mortality and morbidity. The term posttuberculosis lung disorder (PTLD) encompasses various manifestations after successful treatment of tuberculosis, such as respiratory symptoms, decline in respiratory function, residual radiological lesions, exercise intolerance, and reduced health­related quality of life (HRQOL). We aimed to assess the HRQOL in PTLD patients by 36­Item Short Form Health Survey. Our study was conducted on PTLD patients who completed their antituberculosis treatment and presented to the outpatient department with diagnosed PTLD or post pulmonary tuberculosis. A total of 92 patients aged 18­-81 years participated in the study after giving written informed consent. Biomass exposure was statistically significant for mental health components (P < .05). Post pulmonary tuberculosis patients with obstructive airway disease showed decreased HRQOL in both physical and mental health components. Our findings revealed a high prevalence of comorbidities, and no significant association was found between physical and mental health components of HRQOL. Thus, we emphasize the need for psychological counselling, pulmonary rehabilitation, and follow­up as holistic management even after microbiological cure for post pulmonary tuberculosis and suggest early screening of HRQOL to improve people’s standard of living.

туберкулез легкихпоследствия туберкулезаSF-­36качество жизнипоздняя стадия туберкулезаоценка состояния здоровьяpulmonary tuberculosisposttuberculosis sequelaeSF­-36quality of lifelate tuberculosishealth assessmentReferencesAggarwal AN. Quality of life with tuberculosis. J Clin Tuberc Other Mycobact Dis. 2019;17:100121. PMID: 31788563. PMCID: PMC6880022. https://doi.org/10.1016/j.jctube.2019.100121Aggarwal AN. Quality of life with tuberculosis. J Clin Tuberc Other Mycobact Dis. 2019;17:100121. PMID: 31788563. PMCID: PMC6880022. https://doi.org/10.1016/j.jctube.2019.100121World Health Organization. Global Tuberculosis Report 2020. World Health Organization; 2020.World Health Organization. Global Tuberculosis Report 2020. World Health Organization; 2020.World Health Organization. Global Tuberculosis Report 2020. World Health Organization. Accessed April 28, 2023. https://www.who.int/docs/default-source/hq-tuberculosis/global-tuberculosis-report-2020/factsheet.pdfWorld Health Organization. Global Tuberculosis Report 2020. World Health Organization. Accessed April 28, 2023. https://www.who.int/docs/default-source/hq-tuberculosis/global-tuberculosis-report-2020/factsheet.pdfWorld Health Organization. Global Tuberculosis Report 2021. World Health Organization; 2021.World Health Organization. Global Tuberculosis Report 2021. World Health Organization; 2021.World Health Organization. Global Tuberculosis Report 2018. World Health Organization; 2018.World Health Organization. Global Tuberculosis Report 2018. World Health Organization; 2018.India TB Report 2022: Coming Together to End TB Altogether. Central TB Division, Ministry of Health and Family Welfare; 2022.India TB Report 2022: Coming Together to End TB Altogether. Central TB Division, Ministry of Health and Family Welfare; 2022.Singla N, Singla R, Fernandes S, Behera D. Post treatment sequelae of multi-drug resistant tuberculosis patients. Indian J Tuberc. 2009;56(4):206–212. PMID: 20469732.Singla N, Singla R, Fernandes S, Behera D. Post treatment sequelae of multi-drug resistant tuberculosis patients. Indian J Tuberc. 2009;56(4):206–212. PMID: 20469732.Di Naso FC, Pereira JS, Schuh SJ, Unis G. Functional evaluation in patients with pulmonary tuberculosis sequelae. Rev Port Pneumol. 2011;17(5):216–221. (In Portuguese). PMID: 21803536. https://doi.org/10.1016/j.rppneu.2011.06.010Di Naso FC, Pereira JS, Schuh SJ, Unis G. Functional evaluation in patients with pulmonary tuberculosis sequelae. Rev Port Pneumol. 2011;17(5):216–221. (In Portuguese). PMID: 21803536. https://doi.org/10.1016/j.rppneu.2011.06.010Singh B, Chaudhary O. Trends of pulmonary impairment in persons with treated pulmonary tuberculosis. International Journal of Medical Research Professionals. 2015;1(1):8–11.Singh B, Chaudhary O. Trends of pulmonary impairment in persons with treated pulmonary tuberculosis. International Journal of Medical Research Professionals. 2015;1(1):8–11.Chung KP, Chen JY, Lee CH, et al; TAMI Group. Trends and predictors of changes in pulmonary function after treatment for pulmonary tuberculosis. Clinics (Sao Paulo). 2011;66(4):549–556. PMID: 21655745. PMCID: PMC3095809. https://doi.org/10.1590/s1807-59322011000400005Chung KP, Chen JY, Lee CH, et al; TAMI Group. Trends and predictors of changes in pulmonary function after treatment for pulmonary tuberculosis. Clinics (Sao Paulo). 2011;66(4):549–556. PMID: 21655745. PMCID: PMC3095809. https://doi.org/10.1590/s1807-59322011000400005Dhamgaye TM. Post-tuberculosis lung diseases: beyond treatment outcome. J Family Med Prim Care. 2022;11(5):2258–2259. PMID: 35800547. PMCID: PMC9254826. https://doi.org/10.4103/jfmpc.jfmpc_2066_21Dhamgaye TM. Post-tuberculosis lung diseases: beyond treatment outcome. J Family Med Prim Care. 2022;11(5):2258–2259. PMID: 35800547. PMCID: PMC9254826. https://doi.org/10.4103/jfmpc.jfmpc_2066_21Ehrlich RI, Adams S, Baatjies R, Jeebhay MF. Chronic airflow obstruction and respiratory symptoms following tuberculosis: a review of South African studies. Int J Tuberc Lung Dis. 2011;15(7):886–891. PMID: 21477424. https://doi.org/10.5588/ijtld.10.0526Ehrlich RI, Adams S, Baatjies R, Jeebhay MF. Chronic airflow obstruction and respiratory symptoms following tuberculosis: a review of South African studies. Int J Tuberc Lung Dis. 2011;15(7):886–891. PMID: 21477424. https://doi.org/10.5588/ijtld.10.0526McHorney CA, Ware JE Jr, Raczek AE. The MOS 36-Item Short-Form Health Survey (SF-36): II. Psychometric and clinical tests of validity in measuring physical and mental health construct. Med Care. 1993;31(3):247–263. PMID: 8450681. https://doi.org/10.1097/00005650-199303000-00006McHorney CA, Ware JE Jr, Raczek AE. The MOS 36-Item Short-Form Health Survey (SF-36): II. Psychometric and clinical tests of validity in measuring physical and mental health construct. Med Care. 1993;31(3):247–263. PMID: 8450681. https://doi.org/10.1097/00005650-199303000-00006Maguire GP, Anstey NM, Ardian M, et al. Pulmonary tuberculosis, impaired lung function, disability and quality of life in a high-burden setting. Int J Tuberc Lung Dis. 2009;13(12):1500–1506. PMID: 19919767.Maguire GP, Anstey NM, Ardian M, et al. Pulmonary tuberculosis, impaired lung function, disability and quality of life in a high-burden setting. Int J Tuberc Lung Dis. 2009;13(12):1500–1506. PMID: 19919767.Tolba SK, Abd El-Hady AA, Moussa H, Abd Alaal ME, Amin W, Aboelmagd F. Efficacy of pulmonary rehabilitation program in patients with treated pulmonary tuberculosis. Systematic Reviews in Pharmacy. 2021;12(3):516–521.Tolba SK, Abd El-Hady AA, Moussa H, Abd Alaal ME, Amin W, Aboelmagd F. Efficacy of pulmonary rehabilitation program in patients with treated pulmonary tuberculosis. Systematic Reviews in Pharmacy. 2021;12(3):516–521.Duyan V, Kurt B, Aktas Z, Duyan GC, Kulkul DO. Relationship between quality of life and characteristics of patients hospitalised with tuberculosis. Int J Tuberc Lung Dis. 2005;9(12):1361–1366. PMID: 16466059.Duyan V, Kurt B, Aktas Z, Duyan GC, Kulkul DO. Relationship between quality of life and characteristics of patients hospitalised with tuberculosis. Int J Tuberc Lung Dis. 2005;9(12):1361–1366. PMID: 16466059.Unalan D, Soyuer F, Ceyhan O, Basturk M, OzturkA. Is the quality of life different in patients with active and inactive tuberculosis?. Indian J Tuberc. 2008;55(3):127–137. PMID: 18807744.Unalan D, Soyuer F, Ceyhan O, Basturk M, OzturkA. Is the quality of life different in patients with active and inactive tuberculosis?. Indian J Tuberc. 2008;55(3):127–137. PMID: 18807744.

The authors declare that there are no conflicts of interest present.