inovmedИнновационная медицина КубаниInnovative Medicine of Kuban2541-9897Scientific Research Institute – Ochapovsky Regional Clinical Hospital No. 110.35401/2541-9897-2024-9-3-131-138inovmed-891Research ArticleОБЗОРЫREVIEWSНесостоятельность толстокишечного анастомоза: современное состояние проблемы и перспективы ранней диагностикиColonic Anastomotic Leakage: Current State of the Problem and Prospects for Early Diagnosishttps://orcid.org/0000-0001-8476-729XЧерныхМ. А.ChernykhM. A.

Черных Максим Александрович, врач-онколог онкологического отделения № 2

199034, Санкт-Петербург, Университетская набережная, д. 7/9

Maxim A. Chernykh, Oncologist, Oncology Unit No. 2

Universitetskaya naberezhnaya 7/9, Saint Petersburg, 199034

doc.chernykh@mail.ruhttps://orcid.org/0000-0002-2274-8170БелоусовА. М.BelousovA. M.

Белоусов Александр Михайлович, к. м. н., заместитель директора по медицинской части (хирургия и онкология), врач-хирург, онколог

Aleksandr M. Belousov, Cand. Sci. (Med.), Deputy Directorfor Medical Work (Surgery and Oncology), Surgeon, Oncologist,

https://orcid.org/0000-0003-2654-1190ШосткаК. Г.ShostkaK. G.

Шостка Кирилл Георгиевич, к. м. н., заведующий онкологическим отделением № 2, врач-онколог

Kirill G. Shostka, Cand. Sci. (Med.), Head of the OncologyUnit No. 2, Oncologist

Санкт-Петербургский государственный университетРоссияSaint Petersburg State UniversityRussian Federation20243009202403131138Copyright © Черных М.А., Белоусов А.М., Шостка К.Г., 20242024Черных М.А., Белоусов А.М., Шостка К.Г.Chernykh M.A., Belousov A.M., Shostka K.G.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.innovmedkub.ru/jour/article/view/891

Статья посвящена актуальной проблеме несостоятельности толстокишечных анастомозов у пациентов, перенесших резекционные вмешательства по поводу колоректального рака. Описаны факторы риска развития несостоятельности толстокишечных анастомозов, а также подходы к ее диагностике. Особое внимание уделено неинвазивной лабораторной ранней диагностике несостоятельности анастомоза с использованием специфических биохимических маркеров. 

The article discusses the problem of colonic anastomotic leakage in patients who underwent resection for colorectal cancer. We describe risk factors for colonic anastomotic leakage and diagnostic approaches. Particular attention is given to noninvasive early diagnosis of anastomotic leakage using laboratory tests with specific biochemical markers. 

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The authors declare that there are no conflicts of interest present.