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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">inovmed</journal-id><journal-title-group><journal-title xml:lang="ru">Инновационная медицина Кубани</journal-title><trans-title-group xml:lang="en"><trans-title>Innovative Medicine of Kuban</trans-title></trans-title-group></journal-title-group><issn pub-type="epub">2541-9897</issn><publisher><publisher-name>Scientific Research Institute – Ochapovsky Regional Clinical Hospital No. 1</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.35401/2541-9897-2024-9-4-113-119</article-id><article-id custom-type="elpub" pub-id-type="custom">inovmed-995</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Возможности пероральной транспапиллярной холангиоскопии в лечении сложного холедохолитиаза</article-title><trans-title-group xml:lang="en"><trans-title>Possibilities of Peroral Transpapillary Cholangioscopy in Treatment of Complex Choledocholithiasis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5594-5739</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дынько</surname><given-names>В. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Dynko</surname><given-names>V. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Дынько Виктор Юрьевич - к. м. н., заведующий отделением эндоскопии, ККБ № 2; доцент кафедры хирургии № 3 ФПК и ППС, КубГМУ.</p><p>350012, Краснодар, ул. Красных-Партизан, д. 6/2</p></bio><bio xml:lang="en"><p>Victor Yu. Dynko - Cand. Sci. (Med.), Head of the Endoscopy Unit, Regional Clinical Hospital No. 2; Associate Professor at the Surgery Department No. 3, Faculty of Continuing Professional Development and Retraining, Kuban State Medical University.</p><p>ulitsa Krasnykh Partizan 6/2, Krasnodar, 350012</p></bio><email xlink:type="simple">dynko.viktor@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3057-5705</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Габриэль</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Gabriel</surname><given-names>S. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Габриэль Сергей Александрович - д. м. н., профессор кафедры хирургии № 3, КубГМУ; врач-эндоскопист, главный врач, ККБ № 2.</p><p>Краснодар</p></bio><bio xml:lang="en"><p>Sergey A. Gabriel - Dr. Sci. (Med.), Professor at the Surgery Department No. 3, Kuban State Medical University; Endoscopist, Chief Physician, Regional Clinical Hospital No. 2.</p><p>Krasnodar</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7193-4447</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мамишев</surname><given-names>А. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Mamishev</surname><given-names>A. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мамишев Адам Казбекович - врач-эндоскопист отделения эндоскопии.</p><p>Краснодар</p></bio><bio xml:lang="en"><p>Adam K. Mamishev - Endoscopist, Endoscopy Unit, Regional Clinical Hospital No. 2.</p><p>Krasnodar</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7862-8613</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Крушельницкий</surname><given-names>В. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Krushelnitsky</surname><given-names>V. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Крушельницкий Владимир Станиславович - к. м. н., заведующий консультативно-диагностическим центром, первый заместитель главного врача, врач-эндоскопист отделения эндоскопии, ККБ № 2; ассистент кафедры хирургии № 3 ФПК и ППС, КубГМУ.</p><p>Краснодар</p></bio><bio xml:lang="en"><p>Vladimir S. Krushelnitsky - Cand. Sci. (Med.), Head of the Consultative and Diagnostic Center, First Deputy Chief Physician, Endoscopist, Endoscopy Unit, Regional Clinical Hospital No. 2; Assistant Professor at the Surgery Department No. 3, Faculty of Continuing Professional Development and Retraining, Kuban State Medical University.</p><p>Krasnodar</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7733-9780</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кулагин</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kulagin</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кулагин Вячеслав Валерьевич - врач-эндоскопист отделения эндоскопии.</p><p>Краснодар</p></bio><bio xml:lang="en"><p>Vyacheslav V. Kulagin - Endoscopist, Endoscopy Unit, Regional Clinical Hospital No. 2.</p><p>Krasnodar</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0008-5452-9715</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Грицай</surname><given-names>А. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Gritsay</surname><given-names>A. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Грицай Алиса Дмитриевна - студентка 4-го курса, лечебный факультет.</p><p>Краснодар</p></bio><bio xml:lang="en"><p>Alisa D. Gritsay - 4th Year Student, Faculty of General Medicine, Kuban State Medical University.</p><p>Krasnodar</p></bio><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Краевая Клиническая Больница № 2; Кубанский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Regional Clinical Hospital No. 2; Kuban State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Краевая Клиническая Больница № 2</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Regional Clinical Hospital No. 2</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Кубанский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Kuban State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>30</day><month>12</month><year>2024</year></pub-date><volume>0</volume><issue>4</issue><fpage>113</fpage><lpage>119</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Дынько В.Ю., Габриэль С.А., Мамишев А.К., Крушельницкий В.С., Кулагин В.В., Грицай А.Д., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Дынько В.Ю., Габриэль С.А., Мамишев А.К., Крушельницкий В.С., Кулагин В.В., Грицай А.Д.</copyright-holder><copyright-holder xml:lang="en">Dynko V.Y., Gabriel S.A., Mamishev A.K., Krushelnitsky V.S., Kulagin V.V., Gritsay A.D.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.innovmedkub.ru/jour/article/view/995">https://www.innovmedkub.ru/jour/article/view/995</self-uri><abstract><sec><title>Актуальность</title><p>Актуальность: Сложный холедохолитиаз остается актуальной медико-социальной проблемой современной медицины. Данная патология чаще встречается у больных желчнокаменной болезнью и является причиной таких осложнений, как: механическая желтуха, острый и хронический панкреатит, холангит и др. Эффективное лечение патологии зависит от правильного предоперационного обследования, что является весьма трудной задачей. В этом случае основополагающая роль отводится малоинвазивным методам диагностики. Эндоскопическая холангиоскопия представляет собой эффективный и высокоинформативный метод диагностики и лечения заболеваний билиарного тракта, в том числе сложного холедохолитиаза, и во многих случаях является единственным методом обследования, с помощью которого можно поставить достоверный диагноз. Актуальным остается вопрос эффективности и возможностей внедрения данной методики ведущими специалистами по всей стране и миру.</p></sec><sec><title>Цель исследования</title><p>Цель исследования: Обобщение имеющихся литературных данных о возможностях применения метода холангиоскопии в диагностике и лечении сложного холедохолитиаза.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы: Был проведен литературный обзор научных трудов за последние 10 лет с использованием ведущих научных ресурсов PubMed и eLIBRARY с целью анализа наиболее современных медицинских статьей, опубликованных в исследуемой области. Исследования, вкюченные в обзор, основаны на экспериментальной и клинической базах данных. Это позволило нам получить наиболее надежные и достоверные результаты, которые могут быть использованы в дальнейших исследованиях и практической медицине.</p></sec><sec><title>Результаты</title><p>Результаты: В результате проведенного нами обзора было выявлено, что эндоскопическая холангиоскопия имеет значимую клиническую ценность, что подтверждает ее роль как важного диагностического и терапевтического инструмента в дополнение к эндоскопической ретроградной холангиопанкреатографии при лечении сложного холедохолитиаза и требует дальнейшего тщательного исследования.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Background</title><p>Background: Сomplex choledocholithiasis remains an urgent socio-medical problem in modern medicine. This pathology is more common in patients with cholelithiasis and causes such complications as obstructive jaundice, acute and chronic pancreatitis, cholangitis, etc. Effective treatment depends on proper preoperative examination, which is quite challenging. In such cases, minimally invasive diagnostic methods play a fundamental role. Endoscopic cholangioscopy is an effective and highly informative method for diagnosis and treatment of biliary diseases including сomplex choledocholithiasis; in many cases it is the only examination technique that allows for a reliable diagnosis. The effectiveness of this technique and possibilities of its implementation by leading specialists in the Russian Federation and around the world remain important issues.</p></sec><sec><title>Objective</title><p>Objective: To summarize available literature data on possibilities of using cholangioscopy in diagnosis and treatment of сomplex choledocholithiasis.</p></sec><sec><title>Materials and methods</title><p>Materials and methods: We conducted a literature review using PubMed and eLIBRARY. Our goal was to cover the most up-to-date medical articles published on the subject in the past 10 years. Studies included in our review are based on experimental and clinical data. Thus, we obtained the most reliable results that can be used in further research and practice.</p></sec><sec><title>Results</title><p>Results: We found that cholangioscopy has significant clinical value, which confirms its role as an important diagnostic and therapeutic approach in addition to endoscopic retrograde cholangiopancreatography in treatment of complex choledocholithiasis. This technique should be further thoroughly studied.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>патология билиарного тракта</kwd><kwd>холангиоскопия</kwd><kwd>холедохолитиаз</kwd><kwd>пероральная холангиоскопия</kwd><kwd>SpyGlass</kwd></kwd-group><kwd-group xml:lang="en"><kwd>biliary disease</kwd><kwd>cholangioscopy</kwd><kwd>choledocholitiasis</kwd><kwd>peroral cholangioscopy</kwd><kwd>SpyGlass</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Бурдюков М.С., Нечипай А.М. 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