Impact of Viral Myocarditis on the Course of Pregnancy and Delivery
https://doi.org/10.35401/2541-9897-2025-10-1-42-48
Abstract
Background: COVID-19 is mainly a respiratory infection; however, in some cases, it can result in cardiac complications in pregnant women leading to the development of myocarditis.
Material and methods: In 2021-2022 we studied the impact of COVID-19-associated myocarditis on the course of pregnancy in the Republican Perinatal Center (Tashkent, Republic of Uzbekistan). We examined a total of 147 pregnant women with myocarditis (of them, 95 women had COVID-19 while pregnant and 52 women had chronic focal myocarditis). The patients underwent electrocardiography, echocardiography, ultrasonography, and laboratory studies (troponin T1).
Results: COVID-19 in pregnant women can lead to COVID-19-associated myocarditis with signs of circulatory failure (68%), in contrast to chronic focal myocarditis with impaired circulation and chronic heart failure (84.7%). Metabolic changes on echocardiography were more typical of COVID-19-associated myocarditis (group 1) than indolent focal myocarditis (group 2); however, pathological changes were more common in group 2, indicating more pronounced changes in the myocardium of pregnant women with chronic focal myocarditis.
Conclusions: The course of gestation in women with COVID-19-associated myocarditis was characterized by the hypertensive syndrome, increased risk of miscarriage, intrauterine growth restriction, and nonreassuring fetal status, but these complications were less common compared with group 2 with chronic focal myocarditis, in which case operative vaginal delivery is indicated.
About the Authors
Nigora Ju. Muratova
Tashkent State Dental Institute
Uzbekistan
Uzbekistan
Nigora Ju. Muratova, Dr. Sci. (Med.), Associate Professor at the Department of Obstetrics and Gynecology
Mahtumquli ko’chasi, 103, Tashkent, 100000
Guldjahan S. Babadjanova
Tashkent Medical Academy
Uzbekistan
Uzbekistan
Guldjahan S. Babadjanova, Dr. Sci. (Med.), Professor at the Department of Obstetrics and Gynecology
Tashkent
Nilufar A. Urinbaeva
Republican Perinatal Center
Uzbekistan
Uzbekistan
Nilufar A. Urinbaeva, Director
Tashkent
Dildora Ju. Eshonkhodjaeva
Tashkent State Dental Institute
Uzbekistan
Uzbekistan
Dildora Ju. Eshonkhodjaeva, Doctoral Candidate, Department of Obstetrics and Gynecology
Tashkent
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Review
For citations:
Muratova N.J., Babadjanova G.S., Urinbaeva N.A., Eshonkhodjaeva D.J. Impact of Viral Myocarditis on the Course of Pregnancy and Delivery. Innovative Medicine of Kuban. 2025;10(1):42-48. (In Russ.) https://doi.org/10.35401/2541-9897-2025-10-1-42-48
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