Preview

Innovative Medicine of Kuban

Advanced search

Clinical Presentation of Acute Appendicitis in Patients With Agenesis of the Vermiform Appendix

https://doi.org/10.35401/2541-9897-2025-10-1-86-92

Abstract

This article analyzes 10 cases of agenesis of the vermiform appendix with clinical presentation of acute appendicitis. Given that this pathology occurs in 1 of 100000 surgical interventions for acute appendicitis according to the literature, it can be assumed that this number of observations was based on the analysis of the results of 1 million interventions.

The article reports clinical (including intraoperative), laboratory, and imaging findings and gives recommendations for detection of agenesis of the vermiform appendix and treatment of abdominal pain syndrome.

About the Authors

Alexander A. Andreev
Voronezh State Medical University named after N.N. Burdenko
Russian Federation

Alexander A. Andreev, Dr. Sci. (Med.), Professor at the Department of General and Outpatient Surgery

ulitsa Studencheskaya 10, Voronezh, 394036



Alexander A. Glukhov
Voronezh State Medical University named after N.N. Burdenko
Russian Federation

Alexander A. Glukhov, Dr. Sci. (Med.), Head of the Department of General and Outpatient Surgery

ulitsa Studencheskaya 10, Voronezh, 394036



Alexander V. Gorlunov
Voronezh City Clinical Hospital of Emergency Medical Care No. 10
Russian Federation

Alexander V. Gorlunov, Cand. Sci. (Med.), Deputy Chief Physician for Surgical Care

Voronezh



Anastasia Yu. Laptiyova
Voronezh State Medical University named after N.N. Burdenko
Russian Federation

Anastasia Yu. Laptiyova, Assistant Professor at the Department of General and Outpatient Surgery

ulitsa Studencheskaya 10, Voronezh, 394036



Anton P. Ostroushko
Voronezh State Medical University named after N.N. Burdenko
Russian Federation

Anton P. Ostroushko, Cand. Sci. (Med.), Associate Professor at the Department of General and Outpatient Surgery

ulitsa Studencheskaya 10, Voronezh, 394036



References

1. Hammood ZD, SalihAM, Mahal LA, YasYT, Ghaleb HA, Kakamad FH. Agenesis of vermiform appendix; a case report with literature review. Int J Surg Case Rep. 2021;87:106364. PMID: 34562720. PMCID: PMC8473660. https://doi.org/10.1016/j.ijscr.2021.106364

2. Ghali MS, Saleem N, Khalaf MH, et al. Congenital absence of appendix: a rare condition that could result in severe complicationsa review of literature. J Surg Case Rep. 2023;2023(12):rjad661. PMID: 38111487. PMCID: PMC10725790. https://doi.org/10.1093/jscr/rjad661

3. Salim A, Moazzam Z, Ashraf A, Dogar SA, Qazi SH. Congenital absence of the appendix in a child with malrotation. Journal of Pediatric Surgery Case Reports. 2020;60:101530. https://doi.org/10.1016/j.epsc.2020.101530

4. Yohannes B, Abebe K. Appendiceal Agenesis: a very rare intraoperative diagnosis - a case report. Int Med Case Rep J. 2021;14:233–236. PMID: 33859503. PMCID: PMC8043782. https://doi.org/10.2147/IMCRJ.S309192

5. Elias EG, Hults R. Congenital absence of vermiform appendix. Arch Surg. 1967;95(2):257–258. PMID: 16097296. https://doi.org/10.1001/archsurg.1967.01330140095022

6. Chèvre F, Gillet M, Vuilleumier H. Agenesis of the vermiform appendix. Surg Laparosc Endosc Percutan Tech. 2000;10(2):110– 112. PMID: 10789585.

7. Shah TA. A 25-year-old male with appendicular agenesis: A case report and literature review. J Taibah Univ Med Sci. 2016;12(1):75–77. PMID: 31435216. PMCID: PMC6694978. https://doi.org/10.1016/j.jtumed.2016.02.003

8. Tripathy BB. Congenital absence of appendix: a surgeon’s dilemma during surgery for acute appendicitis. J Indian Assoc Pediatr Surg. 2016;21(4):199–201. PMID: 27695217. PMCID: PMC4980886. https://doi.org/10.4103/0971-9261.186555

9. Giron F, Rey Chaves CE, Rodríguez ML, Conde D, Venegas D, Arango A. Appendicular agenesis as an unusual intraoperative finding in acute abdomen: Case report and literature review. Int J Surg Case Rep. 2022;90:106740. PMID: 34974355. PMCID: PMC8728466. https://doi.org/10.1016/j.ijscr.2021.106740

10. Савастюк А.Е., Давыдова Л.А. Морфологические и топографические особенности червеобразного отростка у детей. Молодой ученый. 2021;(44):40–46. Savastsiuk AE, Davydova LA. Morphological features of the vermiform appendix in children. Molodoi uchenyi. 2021;(44):40– 46. (In Russ.).

11. Morgagni G, Lancisi GM, Volpi GB. Adversaria anatomica omnia (Quorum tria posteriora nunc primùm prodeunt) Novis pluribus aereis tabulis, & universali accuratissimo indice ornata. Opus nunc vere absolutum, inventis, & innumeris observationibus, ac monitis refertum, quibus universa humani corporis anatome, & ... res medica, & chirurgica admodum illustrantur. 1719. (In Latin).

12. Sedik A, Al-Dawoodi T, Elhoushy S. Appendicular agenesis: a case report. International Surgery Journal. 2018;5(3): 1121–1123.

13. Глухов А.А., Андреев А.А., Горлунов А.В. и др. Клинический случай отсутствия червеобразного отростка. Вестник экспериментальной и клинической хирургии. 2022;15(2):162– 164. https://doi.org/10.18499/2070-478x-2022-15-2-162-164 Glukhov AA, Andreev AA, Gorlunov AV, et al. Clinical case of absence of the appendix. Journal of Experimental and Clinical Surgery. 2022;15(2):162–164. (In Russ.). https://doi.org/10.18499/2070-478x-2022-15-2-162-164

14. Vincent MV, Doyle A, Bernstein S, Jackman S. Absence of the appendix discovered during childhood. Springerplus. 2014;3:522. PMID: 25279313. PMCID: PMC4166596. https://doi. org/10.1186/2193-1801-3-522

15. Zetina-Mejía CA, Alvarez-Cosío JE, Quillo-Olvera J. Congenital absence of the cecal appendix. Case report. Cir Cir. 2009;77(5):407–410. PMID: 19944032.

16. Nissler V, Fleischmann J, Hümmer HP, Knorr C. Agenesis of the vermiform appendix. J Pediatr Surg. 2012;47(6):1302–1303. PMID: 22703811. https://doi.org/10.1016/j.jpedsurg.2012.03.050

17. Ghali MS, Saleem N, Khalaf MH, et al. Congenital absence of appendix: a rare condition that could result in severe complications-a review of literature. J Surg Case Rep. 2023;2023(12):rjad661. PMID: 38111487. PMCID: PMC10725790. https://doi.org/10.1093/jscr/rjad661.


Review

For citations:


Andreev A.A., Glukhov A.A., Gorlunov A.V., Laptiyova A.Yu., Ostroushko A.P. Clinical Presentation of Acute Appendicitis in Patients With Agenesis of the Vermiform Appendix. Innovative Medicine of Kuban. 2025;10(1):86-92. (In Russ.) https://doi.org/10.35401/2541-9897-2025-10-1-86-92

Views: 131


ISSN 2541-9897 (Online)