Экзосомальная терапия для безрубцового восстановления кожи: клиническое применение и новые тенденции
https://doi.org/10.35401/2541-9897-2025-10-4-121-128
Аннотация
Образование рубцовой ткани остается существенным ограничением традиционных методов лечения ран, нередко приводящим к функциональным нарушениям и эстетическим дефектам. В последние годы экзосомальная терапия рассматривается как новая регенеративная стратегия, способная ускорять заживление ран и снижать уровень формирования фиброза. Наночастицы внеклеточных везикул, полученные из мезенхимальных стволовых клеток, жировой ткани и тромбоцитов содержат биологически активные молекулы, регулирующие воспалительные процессы, стимулирующие ангиогенез и способствующие ремоделированию внеклеточного матрикса. Результаты доклинических и клинических исследований все чаще подтверждают потенциал экзосомальной терапии в стимулировании безрубцовой регенерации кожи. Настоящий обзор направлен на изучение терапевтических применений, клинических достижений и новых тенденций в области экзосомальных технологий кожной регенерации. Также рассматриваются текущие трудности – включая масштабируемость производства, вопросы нормативного регулирования и способы доставки – предлагаются возможные пути для ускорения внедрения в клиническую практику.
Об авторе
Э. Киролос
Хелуанский университет
Египет
Египет
Эскандар Киролос, MBBCh, MA, медицинский работник
Хелуан, мухафаза Каир 4037120
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Рецензия
Для цитирования:
Киролос Э. Экзосомальная терапия для безрубцового восстановления кожи: клиническое применение и новые тенденции. Инновационная медицина Кубани. 2025;10(4):121-128. https://doi.org/10.35401/2541-9897-2025-10-4-121-128
For citation:
Kirolos E. Exosome-Based Therapies for Scar-Free Skin Regeneration: Clinical Applications and Emerging Trends. Innovative Medicine of Kuban. 2025;10(4):121-128. https://doi.org/10.35401/2541-9897-2025-10-4-121-128
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