Rupture of a Middle Cerebral Artery Aneurysm 11 Years After Diagnosis Verification
https://doi.org/10.35401/2541-9897-2026-11-1-100-107
Abstract
Unruptured cerebral aneurysms are detected in 3–5% of the adult population. Aneurysm rupture results in intracranial hemorrhage, with a mortality rate of approximately 45% and disability in about 30% of cases. Risk assessment scales for rupture of unruptured aneurysms (UCAS, ISUIA, PHASES, UIATS, ELAPSS) were developed to guide treatment strategy; however, their practical application has revealed a systematically underestimation of hemorrhage risk. In particular, a meta-analysis of more than 1,500 cases of aneurysmal hemorrhage demonstrated that 50–80% of the observed aneurysms had initially been classified as low risk, indicating significant limitations of current rupture risk assessment tools and highlighting the need for the development of dynamic models to predict hemorrhage probability that account for changes in clinical status and aneurysm morphology over time.
The presented clinical case of middle cerebral artery aneurysm management illustrates the necessity to transform current approaches to determining treatment strategies for unruptured aneurysms.
About the Authors
M. E. Pershin
Scientific Research Institute – Ochapovsky Regional Clinical Hospital No. 1
Russian Federation
Russian Federation
Mikhail E. Pershin - Neurosurgeon, Neurosurgical Department No. 2, Scientific Research Institute – Ochapovsky Regional Clinical Hospital No. 1.
Krasnodar
A. D. Fedorenko
Kuban State Medical University
Russian Federation
Russian Federation
Arkady D. Fedorenko - Resident in Neurosurgery, Department of Neurology and Neurosurgery, Kuban State Medical University.
Krasnodar
D. V. Litvinenko
Scientific Research Institute – Ochapovsky Regional Clinical Hospital No. 1
Russian Federation
Russian Federation
Dmitry V. Litvinenko - Cand. Sci. (Med.), Neurosurgeon, Neurosurgical Department No. 2, Scientific Research Institute – Ochapovsky Regional Clinical Hospital No. 1.
167 1 Maya St., Krasnodar, 350086
A. V. Dubovoy
Ilyinskaya Hospital
Russian Federation
Russian Federation
Andrey V. Dubovoy - Leading Neurosurgeon, Ilyinskaya Hospital.
Moscow region, Krasnogorsk city district, Glukhovo village
E. I. Zyablova
Scientific Research Institute – Ochapovsky Regional Clinical Hospital No. 1; Kuban State Medical University
Russian Federation
Russian Federation
Elena I. Zyablova - Dr. Sci. (Med.), Head of the Radiology Department, Scientific Research Institute – Ochapovsky Regional Clinical Hospital No. 1.
Krasnodar
V. V. Tkachev
Scientific Research Institute – Ochapovsky Regional Clinical Hospital No. 1; Kuban State Medical University
Russian Federation
Russian Federation
Vyacheslav V. Tkachev - Dr. Sci. (Med.), Head of Neurosurgical Department No. 2, Scientific Research Institute – Ochapovsky Regional Clinical Hospital No. 1; Professor, Department of Neurology and Neurosurgery, Kuban State Medical University.
Krasnodar
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Review
For citations:
Pershin M.E., Fedorenko A.D., Litvinenko D.V., Dubovoy A.V., Zyablova E.I., Tkachev V.V. Rupture of a Middle Cerebral Artery Aneurysm 11 Years After Diagnosis Verification. Innovative Medicine of Kuban. 2026;11(1):100-107. (In Russ.) https://doi.org/10.35401/2541-9897-2026-11-1-100-107
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