Microbiome in Prostate Cancer
https://doi.org/10.35401/2541-9897-2026-11-2-101-108
Abstract
Changes in the composition of the native microbiome may contribute to tumor development, as chronic infections, viral genetic integration, and microbial metabolites can potentially influence carcinogenesis, including in the prostate. Studies employing sequencing have revealed associations between the microbiome composition in the genitourinary system, gastrointestinal tract, and oral cavity and the risk of development and progression of prostate cancer.
This review focuses on the analysis and integration of current data on the role of the microbiota in the pathogenesis of prostate cancer. Further investigation in this area may enhance diagnostic capabilities and inform future treatment and prevention paradigms.
Supporting agencies: This work was supported by the Strategic Academic Leadership Program of the University (Priority-2030)
About the Authors
V. N. Pavlov
Bashkir State Medical University
Russian Federation
Russian Federation
Valentin N. Pavlov - Dr. Sci. (Med.), Professor, Academician of the Russian Academy of Sciences, Head of the Urology and Oncology Department.
3 Lenina St., Ufa, 450077
I. A. Gimranova
Bashkir State Medical University
Russian Federation
Russian Federation
Irina A. Gimranova - Cand. Sci. (Med.), Associate Professor, Head of the Department of Fundamental and Applied Microbiology.
Ufa
G. R. Gazizullina
Bashkir State Medical University
Russian Federation
Russian Federation
Gulnara R. Gazizullina - Head of the Laboratory of Human Microbiome.
Ufa
D. Yu. Shvets
Institute of Biochemistry and Genetics of the Ufa Federal Research Center of the Russian Academy of Sciences
Russian Federation
Russian Federation
Darya Yu. Shvets - Postgraduate Student (4th year), Institute of Biochemistry and Genetics.
Ufa
Z. A. Ibragimova
Bashkir State Medical University
Russian Federation
Russian Federation
Zarina A. Ibragimova - Junior Researcher, Laboratory of the Human Microbiome.
Ufa
D. Z. Zaiceva
Bashkir State Medical University
Russian Federation
Russian Federation
Diana Z. Zaiceva - Junior Researcher, Laboratory of the Human Microbiome.
Ufa
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For citations:
Pavlov V.N., Gimranova I.A., Gazizullina G.R., Shvets D.Yu., Ibragimova Z.A., Zaiceva D.Z. Microbiome in Prostate Cancer. Innovative Medicine of Kuban. 2026;11(2):101-108. (In Russ.) https://doi.org/10.35401/2541-9897-2026-11-2-101-108
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