Age-dependent changes of coagulation system parameters in pediatric patients of cardiosurgical profile
https://doi.org/10.35401/2500-0268-2020-17-1-23-29
Abstract
Objective. Estimate baseline coagulation profile values in patients scheduled for cardiosurgical intervention in age groups of pediatric population.
Material and Methods. The coagulation profile was analyzed in a complete selection of patients admitted to the intensive care department of Scientific Research Institute – Ochapovsky Regional Clinical Hospital no. 1 for the period from January to December 2018. The study includes 842 patients planned for cardiac surgery.
Results. This study demonstrates the dependence of the basic parameters of the hemostasis system on age characteristics, mainly during the period of the first year of life. APPT values were similar in all age groups, whereas extended PV was recorded in patients less than one year.
Conclusion. Evaluation of coagulation system parameters should be based on age-specific reference values. Understanding the concept of developing hemostasis is extremely important in conditions of optimal prevention, diagnosis and treatment of hemorrhagic and thrombotic conditions in the pediatric population.
About the Authors
N. B. Karakhalis
Scientific Research Institute – Ochapovsky Regional Clinical Hospital no. 1; Kuban State Medical University
Russian Federation
Russian Federation
Nikolay B. Karakhalis, Cand. of Sci. (Med.), Head of Anaesthesiology and Resuscitation no. 9; Associate Professor of Anaesthesiology, Resuscitation and Transfusiology Department for Advanced Training
167, 1st May str., Krasnodar, 350086
A. Kh. Kade
Kuban State Medical University
Russian Federation
Russian Federation
Azamat Kh. Kade, Dr. of Sci. (Med.), Professor, Head of General and Clinical Pathophysiology Department
A. V. Bratova
Scientific Research Institute – Ochapovsky Regional Clinical Hospital no. 1
Russian Federation
Alla V. Bratova, Head of Clinical Diagnostic Laboratory
Russian Federation
Alla V. Bratova, Head of Clinical Diagnostic Laboratory
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Review
For citations:
Karakhalis N.B., Kade A.Kh., Bratova A.V. Age-dependent changes of coagulation system parameters in pediatric patients of cardiosurgical profile. Innovative Medicine of Kuban. 2020;(1):23-29. (In Russ.) https://doi.org/10.35401/2500-0268-2020-17-1-23-29
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