Risk stratification of thromboembolic complications development in surgical patients
https://doi.org/10.35401/2500-0268-2020-17-1-46-51
Abstract
Aim. Creating a mathematically based scale of risk stratification of thromboembolic complications in patients with acute abdominal organs pathology requiring urgent surgical treatment.
Material and Methods. This work is based on data from 185 case reports of patients with acute surgical diseases of the abdominal organs that had undergone emergency operations. Clinical and statistical analyses were carried out and the most significant risk factors for venous thromboembolic complications were identified. By digitally estimating the specific gravity of each of the factors, the method of sequential probability ratio criterion was applied to the obtained data.
Results and Discussion. Based on a retrospective analysis of clinical records, 13 most informative prognostic criteria for thromboembolic complications formed in the prognostic table were identified. Each sign, depending on its value, had a specific gravity. For the convenient using of the prognostic scale in practice, the indicators of natural logarithms are translated into arbitrary units (points). The results are checked on available archival records. The overall forecast reliability was 97%.
Conclusion. The proposed prognostic scale made it possible to optimize the likelihood of a feasibility study in patients with acute diseases of the abdominal organs.
About the Authors
K. I. PopandopuloRussian Federation
Konstantin I. Popandopulo, Dr. of Sci. (Med.), Head of Theoretical and Hospital Surgery Department
V. A. Porhanov
Russian Federation
Vladimir A. Porhanov, Dr. of Sci. (Med.), Professor, Academician of RAS, Head of Oncological Department with a Course of Thoracic Surgery for Advanced Training; Head Doctor
G. K. Karipidi
Russian Federation
Gennady K. Karipidi, Dr. of Sci. (Med.), Professor of Theoretical and Hospital Surgery Department
I. V. Vagin
Russian Federation
Ivan V. Vagin, Postgraduate Student of Theoretical and Hospital Surgery Department; Surgeon
167, 1st May str., Krasnodar, 350086
S. B. Bazlov
Russian Federation
Sergey B. Bazlov, Cand. of Sci. (Med.), Associate Professor of Theoretical and Hospital Surgery Department
A. Yu. Popov
Russian Federation
Arsen Yu. Popov, Head of Surgical Department no. 1
References
1. Tarabrin OA, Shcherbakov SS. Features of diagnosis of hemostatic disorders and optimization of infusion therapy for severe destructive pancreatitis. Meditsina neotlozhnykh sostoyanij. 2014;2(57):40-4. (In Russ.).
2. Kruchinina MV, Gromov AA, Rabko AV, Abdullaeva PA, et al. Aspirin resistence as a risk marker for venous thromboembolic complications. Ateroskleroz. 2018;14(4):40-55. (In Russ.). DOI: 10.15372/ater20180405
3. Buryachkovskaya LI, Lomakin NV, Sumarokov AB, Shirokov EA. Efficacy and safety of antithrombic therapy [venous thrombosis and pulmonary artery thrombembolia]: scales and algorithms. Terapiya. 2019;5(4(30)):10-20. (In Russ.). DOI: 10.18565/therapy.2019.4.10-20
4. Barinov VE, Lobastov KV, Schastlivtsev IV, Tsaplin SN, et al. Predictors of venous thromboembolism in the high risk surgical patients. Flebologiya. 2014;8(1):21-32. (In Russ.).
5. Boyarintsev VV, Alencheva EV, Lobastov KV, Barinov VE. The intermitting pneumatic compression as a component of complex prophylactic measures to prevent postoperative venous thromboembolytic complications. Kremlevskaya medicina. Klinicheskij vestnik. 2016;2:12-9. (In Russ.).
6. Pestrikova TYu, Yurasova EA, Yurasov IV, Knyazeva TP, Tkachenko VA. Prevention of thromboembolism. Rational approach of maintaining patients in the postoperative period (review). Consilium Medicum. 2018;20(6):53-6 (In Russ.). DOI: 10.26442/2075-1753_2018.6.53-56
7. Digbi ZhK, Kukla P, Chzhon-Kyun Ch, Pastore K. The value of electrocardiographic abnormalities in the prognosis of pulmonary embolism: a consensus paper. Kardiologiya: novosti, mneniya, obuchenie. 2016;2(9):59-76. (In Russ.).
8. Alencheva E, Lobastov K, Barinov V, Brekhov E, et al. Combined pharmacomechanical prevention of postoperative venous thromboembolic events. Vrach. 2018;29(5):55-8. (In Russ.). DOI: 10.29296/25877305-2018-05-13
9. Silina EV, Kabaeva EN, Stupin VA, Tyazhelnikov AA, et al. Venous thromboembolic complications in stroke. Patogenez. 2018;16(2):70-7. (In Russ.). DOI: 10.25557/2310-0435.2018.02.70-77
10. Konstantinides SV, Torbicki A, Agnelli G, et al. 2014 ESC Guidelines on the diagnosis and management of acute pulmonary embolism: The Task Force for the Diagnosis and Management of Acute Pulmonary Embolism of the European Society of Cardiology (ESC). Endorsed by the European Respiratory Society (ERS). Eur Heart J. 2014;35(43):3033-80. DOI: 10.1093/eurheartj/ehu283
11. Lobastov K, Barinov V, Schastlivtsev I, et al. Validation of the Caprini risk assessment model for venous thromboembolism in high-risk surgical patients in the background of standard prophylaxis. J Vascular Surg Venous Lymphat Disord. 2016;4(2):153-60. DOI: 10.1016/j.jvsv.2015.09.004
12. Patel K, Chun LJ, Brenner BE, Chang JS. Deep Venous Thrombosis (DVT). URL: https://emedicine.medscape.com/article/1911303-overview (accessed: 16.02.2020).
Review
For citations:
Popandopulo K.I., Porhanov V.A., Karipidi G.K., Vagin I.V., Bazlov S.B., Popov A.Yu. Risk stratification of thromboembolic complications development in surgical patients. Innovative Medicine of Kuban. 2020;(1):46-51. (In Russ.) https://doi.org/10.35401/2500-0268-2020-17-1-46-51