Hernia or hernia Defect? Experimental herniology Models in Laboratory Animals
https://doi.org/10.35401/2541-9897-2023-26-3-114-120
Abstract
Hernias of the anterior abdominal wall remain one of the most common surgery pathologies. There is no unified approach to modeling anterior abdominal wall hernias in the world scientific community. In order to systematize the available knowledge in this field and to contribute to the formation of a unified idea of how to create a hernia model in a laboratory animal, it seems logical to study the accumulated experience of researchers in the field of experimental herniology. We found out that hernia defects generally modeled on male laboratory rats. To understand the tissue reaction to the prosthetic material a fenestration was performed in the anterior abdominal wall (including peritoneum) except for the skin and subcutaneous fat. A replacement or prosthetic material tailored to the fenestration was sutured end-to-end into the abdominal wall. We chose laboratory rats because they are easy to take care of and cheaper than larger laboratory animals.
About the Authors
V. A. Lazarenko
Kursk State Medical University
Russian Federation
Russian Federation
Viktor A. Lazarenko, Dr. Sci. (Med.), Professor, Rector
Kursk
I. S. Ivanov
Kursk State Medical University
Russian Federation
Russian Federation
Ilia S. Ivanov, Dr. Sci. (Med.), Professor, Head of the Department
Surgical Diseases Department No. 1
Kursk
A. A. Ushanov
Kursk State Medical University
Russian Federation
Russian Federation
Alexander A. Ushanov, Postgraduate Student
305041
ulitsa K. Marksa 3
Kursk
E. S. Mishina
Kursk State Medical University
Russian Federation
Russian Federation
Ekaterina S. Mishina, Cand. Sci. (Med.), Associate Professor
Department of Histology, Embryology and Cytology
Kursk
E. G. Obedkov
Kursk State Medical University
Russian Federation
Russian Federation
Evgenij G. Obedkov, Cand. Sci. (Med.), Assistant Professor
Surgical Diseases Department No. 1
Kursk
V. S. Kostin
Kursk State Medical University
Russian Federation
Russian Federation
Viktor S. Kostin, 5th Year Student
Kursk
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Review
For citations:
Lazarenko V.A., Ivanov I.S., Ushanov A.A., Mishina E.S., Obedkov E.G., Kostin V.S. Hernia or hernia Defect? Experimental herniology Models in Laboratory Animals. Innovative Medicine of Kuban. 2023;(3):114-120. (In Russ.) https://doi.org/10.35401/2541-9897-2023-26-3-114-120
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