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Adverse Events in the Treatment of Cancer Patients: Neurotoxicity, Vasculitis, Encephalitis, and Aseptic Meningitis

Abstract

Adverse events affecting the central and peripheral nervous systems of associated with antitumor therapy, including radiation therapy, immunotherapy, and chemotherapy, remain a complex diagnostic and clinical challenge. Magnetic resonance imaging (MRI) is the main tool for assessing central neurotoxicity, allowing prevention of tumor progression, infectious and drug-induced changes, and vascular lesions. This article reviews current data on the pathogenesis, clinical manifestations, and typical MRI patterns of the main cerebral complications of cancer treatment.

About the Authors

S. G. Gvindzhiia
Scientific Research Institute – Ochapovsky Regional Clinical Hospital No. 1; Kuban State Medical University
Russian Federation

Elena I. Zyablova, Dr. Sci. (Med.), Associate Professor Head of the Department of Radiation Diagnostics No. 2; Head of the X-ray Department; Chief Freelance Radiologist of the Ministry of Health of the Krasnodar Region

167 1 Maya St., Krasnodar, 350086



E. Yu. Krivitskaya
Scientific Research Institute – Ochapovsky Regional Clinical Hospital No. 1; Kuban State Medical University
Russian Federation

Elena Yu. Krivitskaya, Radiologist X-ray Department; Assistant, Department of Radiation Diagnostics No. 2

Krasnodar



E. I. Zyablova
Scientific Research Institute – Ochapovsky Regional Clinical Hospital No. 1; Kuban State Medical University
Russian Federation

Saria G. Gvindzhiia, Radiologist, X-ray Department; Assistant Professor, Department of Radiation Diagnostics No. 2

Krasnodar



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Review

For citations:


Gvindzhiia S.G., Krivitskaya E.Yu., Zyablova E.I. Adverse Events in the Treatment of Cancer Patients: Neurotoxicity, Vasculitis, Encephalitis, and Aseptic Meningitis. Innovative Medicine of Kuban. 2026;11(1-1):19-26. (In Russ.)

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