ANALYSIS OF PREVENTION AND TREATMENT FOR MULTI-ORGAN FAILURE SYNDROME IN HARD BURNT PATIENTS
Abstract
Background. We discussed main issues regarding pathogenesis of burn disease and development of multi-organ failure and identified basic methods for prevention and improvement.
Objectives. We studied possible prevention of multi-organ failure syndrome.
Material and methods. We presented analysis of treatment in hard-burnt patients for 10 years. This analysis included 643 compromised patients with deep burns. They were treated in Samarkand Branch of RNTEMP from 2008 to 2018, age range was 18–74 years. All patients were divided into 2 groups regarding their treatment method. Control group included 313 (48.67%) patients treated in Burn Department of Samarkand Branch of RNTEMP for the period 2008–2012.
Their complex treatment included routine anti-shock infusion-transfusion therapy and conventional management regarding burn disease stages. Main group consisted of 330 (51.33%) patients with the same pathology referred to Samarkand Branch of RNTEMP during the period 2013–2018. They were treated with improved procedure of anti-shock infusion-transfusion therapy with inotropic and organo-saving support according to disorders of vital functions and early active surgical technique.
Results. It is shown that implementation of advanced complex intensive infusion-transfusion therapy, application of organ-saving therapy, correction of the compromised premorbid background, and nutritional support as well facilitate shock manifestation, reduce number of patients with multi-organ insufficiency and mortality in hard-burnt cohort.
About the Author
E. A. Khakimov
Samarkand State Medical Institute; Samarkand Branch Establishment RNTEMP
Uzbekistan
Uzbekistan
Cand. of Sci. (Med.), Head of the Combustiology Department
Samarkand Branch Establishment RNTEMP, 98-2, Rudaki str., Samarkand, 140120
References
1. Alekseev A.A., Krutikov M.G., Shlyk I.V. et al. Diagnosis and treatment of burn shock: clinical guidelines. All-Russian public organization «Association of combustiologists «World without burns». Moscow, 2014. 17 p. (In Russ.).
2. Ermolov S.V., Smirnov S.V., Gerasimova L.I. et al. Polyorgan failure Syndrome in burned patients: problems of diagnosis, prevention and treatment. Kombustiologiya. 2003;1:71-76. (In Russ.).
3. Krylov K.M., Shlyk V.I., Pivovarova L.P., Orlova O.V. Burn shock In the book Pathogenesis and treatment of shock of various etiologies: manual for doctors. St. Petersburg, 2010. pp. 320-360. (In Russ.).
4. Zhilinsky E. V. methods of predicting sepsis in burn disease. Sat. proceedings of the V Congress of combustiologists of Russia «Thermal lesions and their consequences», Moscow (October 31 – November 3), 2017. p. 74-75. (In Russ.).
5. Spiridonova T.G., Smirnov S.V. Systemic inflammatory response and multiple organ dysfunction and insufficiency in burned. Man. scientific works of The I Congress of combustiologists of Russia «world without burns», Moscow, October 17-21, 2005. р. 98-99. (In Russ.).
6. Taran A.V. The Syndrome of multi organ insufficiency in the burned-problems of clinical diagnosis and treatment. Sat. scientific works of The I Congress of combustiologists of Russia «world without burns», Moscow, October 17-21, 2005. pp. 102-103. (In Russ.).
7. Wagner D.O., Krylov K.M., Soloshenko V.V. Results of early surgical treatment of victims with extensive deep burns. Sb. proceedings of the V Congress of combustiologists of Russia «Thermal lesions and their consequences», Moscow (October 31 – November 3), 2017. p. 41-42. (In Russ.).
Review
For citations:
Khakimov E.A. ANALYSIS OF PREVENTION AND TREATMENT FOR MULTI-ORGAN FAILURE SYNDROME IN HARD BURNT PATIENTS. Innovative Medicine of Kuban. 2019;(1):28-35. (In Russ.)
Views:
451
Email this article 
