Preview

Innovative Medicine of Kuban

Advanced search

Once again on spasticity in neurology (literature review)

Abstract

Now it is difficult to give exhaustive definition for spasticity taking into account its formation mechanisms as the neurobiology of the locomotion system is not studied regarding several aspects. The long term solution of this task will allow to define separate kinds of muscular hypertension, known for experts under the general name as a spasticity syndrome. At the same time for neurologists phenomenologically it is a rather clear question. Spastic paresis is the main reason of disability in neurologic patients as it develops in a great majority of diseases and damages of CNS. At the same time it limits physical activity in a patient by itself, but the expressed spasticity considerably aggravates motive violations, even more reducing functionality in a patient. While discussing approaches for spasticity treatment it is necessary to consider that this phenomenon is a very dynamic one. In this regard therapy of similar patients should be not only individual and carefully planned, but also constantly being monitored. Patients with spastic paresis require long-term treatment therefore it is necessary to reconsider the purposes and problems of therapy regularly, to define new boundaries and to specify old ones. It is especially important in a case with prolonged usage of muscle relaxants. The main treatment of a spastic muscular hypertension is a medical treatment. At the same time muscle relaxants are used both as monotherapy, and as a part of the general rehabilitation strategy. These drugs provide useful basic effect which allows to stack the paralyzed extremity in the most comfortable position or use the orthosis adequately. Thus, muscle relaxants impact a great number of neurophysiological and neurochemical mechanisms taking part in spasticity formation which provides their more significant efficiency.

About the Authors

M. A. Barabanova
Kuban State Medical University, Ministry of Health of the Russian Federation
Russian Federation


O. V. Stoyanova
Kuban State Medical University, Ministry of Health of the Russian Federation
Russian Federation


T. A. Petropavlovskaya
Kuban State Medical University, Ministry of Health of the Russian Federation
Russian Federation


D. O. Kardailskaya
Kuban State Medical University, Ministry of Health of the Russian Federation
Russian Federation


References

1. Бархатова В.П. и др. Спастический синдром в неврологии. Возможности толперизона// Рус. мед. журн. 2005. Т. 13. № 22. С. 1503.

2. Вейн А.М., Воробьева О.В. Болезненный мышечный спазм и спастичность. Алгоритм диагностики и терапии// Рус. мед. журн. 2003. Т. 11. № 8. С. 438.

3. Гусев Е.И., Гехт А.Б. Спастичность. Рус. мед. журн. 1999. Т. 7. № 12. С. 567.

4. Гранит Р. Основы регуляции движений. М., 1973.

5. Дамулин И.В. Синдром спастичности и основные направления его лечения // Журн. Неврологии и психиатрии им. С.С. Корсакова. 2003. № 12, с.4-9.

6. Данилов А.Б. Возможности применения тизанидина (Сирдалуда) в клинической практике. Обзор литературы// Русский медицинский журнал. - 2010. - № 1, с.4-10.

7. Завалишин И. А., Стойда Н. И., Шитикова И. Е. Клиническая характеристика синдрома верхнего мотонейрона. В кн.: Синдром верхнего мотонейрона. Под ред. И. А. Завалишина, А. И. Осадчих, Я. В. Власова. Самара: Самарское отд. Литфонда, 2005. С. 11-54.

8. Завалишин И.А., Бархатова В.П. Спастичность. Журн. неврол. психиатр.им. С.С. Корсакова. 1997. Т. 97. № 3. С. 68-72.

9. Касаткин Д.С. // Журн. неврол. психиатр. им. С.С. Корсакова. 2008. Т. 108. № 3. С. 80.

10. Кадыков А. С., Черникова Л. А., Шахпаронова Н. В. Реабилитация неврологических больных. М.: МЕДпресс-информ, 2009. 560 с.

11. Кадыков А. С., Шахпаранова Н. В. Медикаментозная реабилитация больных со спастическими парезами. В кн.: Синдром верхнего мотонейрона. Под ред. И. А. Завалишина, А. И. Осадчих, Я. В. Власова. Самара: Самарское отд. Литфонда, 2005.

12. Клюшников С.А., Иллариошкин С.Н., Иванова-Смоленская И.А. Спастический синдром в неврологии. Возможности толперизона (мидокалма) в терапии спастических проявлений нейроваскулярных синдромов//Атмосфера. 2009. №3, с.39-41.

13. Лунев Д.К. Нарушения мышечного тонуса при мозговом инсульте. М., 1974.

14. Парфенов В.А. Ведение больных со спастичностью // Рус. мед.журнал.- 2004.- Т.12, №10.

15. Парфенов В.А. Патогенез и лечение спастичности//Русский медицинский журнал. 2011. Т.9. №25, с.16-18.

16. Парфенов В.А. Постинсультная спастичность и ее лечение // Русский медицинский журнал. -2006. Т. 14. №9.

17. Филатова Е.Г., Соловьева А.Д., Данилов А.Б. Лечение головной боли напряжения // Журнал неврол. и психиатр. 1996, 4, 21-25.

18. Штульман Д. Р., Левин О. С. Неврология: справочник практикующего врача. 5-е изд., доп. и перераб. М.: МЕД прессинформ, 2007. 960 с.

19. Ashby P. et al. // Brain. 1972. V. 95. P. 21.

20. Barnes M.P. // Age Ageing. 1998. V. 27. P. 239.

21. Chesselet M.F., Delfs J.M. // Trends Neurosci. 1996. V 19. P. 417.

22. Coward D.M. Tizanidine: Neuropharmacology and mechanism of action. Neurology 1994; 44 (Suppl. 9): 6-11.

23. Davidoff R.A. Spinal neurotransmitters and the mode of action of antispasticity drugs // The Origin and Treatment of Spasticity / Ed. by Benecke R. et al. Carnforth, 1990. P. 63.

24. Delzell JE Jr, Grelle A.R. Trigeminal neuralgia. New treatment options for a well-known cause of facial pain. Arch Fam Med 1999 May-Jun; 8 (3): 264-8.

25. Freitag F.G. Preventative treatment for migraine and tension-type headaches: do drugs having effects on muscle spasm and tone have a role? CNS Drugs 2003; 17 (6): 373-81.

26. Gracies J.-M. , Pathophysiology of spastic paresis. Emergence of muscle overactivity. Muscle & Nerve. 2005. V 31. P. 552.

27. Leiphart J.W., Dills C.V., Levy R.M. Alpha2 - adrenergic receptor subtype specificity of intrathecally administered tizanidine used for analgesia for neuropathic pain // J Neurosurg. 2004; 101(24): 641-647.

28. Manfredini D., Romagnoli M., Cantini E., Bosco M. Efficacy of tizanidine hydrochloride in the treatment of myofascial face pain. Minerva Med 2004 Apr; 95 (2): 165-71.

29. Noth J. Trends in the pathophysiology and pharmacotherapy of spasticity. J. Neurol. 1991. V. 238. P. 131-139.

30. Smith B.H., Sweet W.H. // Neurosurgery. 1978. V. 3. P. 109.


Review

For citations:


Barabanova M.A., Stoyanova O.V., Petropavlovskaya T.A., Kardailskaya D.O. Once again on spasticity in neurology (literature review). Innovative Medicine of Kuban. 2016;(2):42-45. (In Russ.)

Views: 340


ISSN 2541-9897 (Online)